鼻咽癌患者放射治疗后性功能减退吗?  

Is there a sexual function decline in nasopharyngeal carcinoma survivors treated with radiotherapy?

作　　者：林志雄[1] 李德锐[1] 陈世坚[1] 史永义[1] 郑明章[1] 

机构地区：[1]广东省汕头大学医学院肿瘤医院鼻咽癌专科,515031

出　　处：《中华放射肿瘤学杂志》2003年第B02期52-55,共4页Chinese Journal of Radiation Oncology

摘　　要：目的　调查鼻咽癌患者放射治疗后的性功能状态 ,了解发生性功能改变的可能影响因素 ,探讨防治性功能障碍、提高放射治疗后生活质量的对策。方法　根据SOMA/LENT表有关性功能内容和研究需要制作统一问卷 ,对 90例 (男性 6 6例 ,女性 2 4例 )符合条件的鼻咽癌患者进行调查。结果　治疗后完全停止性生活 4例 ( 4.4% ) ,1年后才恢复性生活 15例 ( 16 .7% ) ;性欲减退占 37.8% ,满意度低占 40 .0 % ,勃起障碍占 7.6 % ,高潮减退占 30 .0 % ,频率减少占 71.1%。患者主观上认为治疗后不宜性生活的主要原因有 :妨碍身体康复 5 7例 ( 6 3.3 % ) ;容易引起肿瘤复发 44例 ( 48.8% ) ;肿瘤会传染爱人 45例 ( 5 0 .0 % ) ;治疗后身体虚弱 2 7例 ( 30 .0 % )。职业、文化程度和经济状况与放射治疗后性功能的改变无明显关系。结论　在放射治疗后的鼻咽癌患者中 ,相当一部分存在明显的性功能障碍 ,普遍存在对性生活的错误认知 ,需要予以心理干预。Objective The want of study about the effect of definitive radiotherapy (RT) on sexual function for nasopharyngeal carcinoma (NPC) led to this investigation. This was designed as a pilot study to assess the patterns of sexual dysfunction and its prevention. Methods Based on the SOMA/LENT toxicity criteria, a standardized questionnaire was designed to investigate the following sexual performances: desire, satisfaction, erectability, orgasm and frequency of sex in the two years before and after radiotherapy with each patient serving as his or her own control. Ninety patients(66 male,24 female) were included into this study. Reduction of libido, satisfaction with sex, erectability, resumption of sex after radiotherapy, intensity of orgasm, frequency of sex and the subjective assumption of sex dysfunction by the patient were all entered and analyzed by the SOMA/LENT .Occupation: 27 workers, 39 farmers, 10 civil servants and 14 businessmen. Thirteen patients had had high school education or above, while the other 77 were on lower level. Results All patients could remember the time of first sexual activity after treatment, 45 of them after 3 months, 71 after one year and 4 patients ceased sex at all. Fifteen patients were able to resume sex one year after radiotherapy. As for the quality of the sexual activity, 34 (37.8%) patients noted a decline in libido, 36 (40.0%) were dissatisfied with their sex and 5(7.6%) of the 66 male patients developed new impotence and 27 (30.0%) complained of lowered intensity of orgasm. The sexual frequency in this cohort was (1.271±0.877)times/week before and ( 0.691±0.854 )times/week after the treatment. Sixty-four (71.1%) patients experienced a frequency diminution. Only 15 experienced no change in their sex. Statistical analysis did not show any significant relation between kinds of profession, education level or economic status and sexual dysfunction, subjective perception. However, subjective perception had a significant impact on the decrease of libido, satisfaction, erec

关 键 词：鼻咽癌 放射疗法 性功能障碍 

分 类 号：R739.63[医药卫生—肿瘤]