补阳还五汤加减治疗脂肪肝59例临床疗效观察  

Clinical Observation on Therapeutic Effect of Adjusted Buyang Huanwu Decoction on 59 Cases with Fatty Liver

作　　者：王昌明[1] 史永奋[1] 王丹华[1] 

机构地区：[1]上海第二医科大学附属仁济医院中医科,上海200001

出　　处：《中国中西医结合消化杂志》2003年第2期88-89,共2页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

摘　　要：目的 :观察补阳还五汤治疗脂肪肝的疗效 ,探索其抗肝纤维化的临床应用价值。方法 :脂肪肝 89例分为两组 ,治疗组 5 9例 ,服用补阳还五汤加减汤方 ;对照组 30例 ,服用丹参片和多烯康胶丸。观察临床疗效并检测治疗前后透明质酸、球蛋白、谷丙转氨酶和 B超的变化情况。结果 :治疗后两组生化指标均有所下降 ,差异有显著性意义 (P <0 .0 1) ;治疗组总有效率为 96 .4 % ,对照组 76 .7% ,两组比较差异有显著性意义 (P <0 .0 1)。结论 :补阳还五汤加减汤方能够显著改善脂肪肝的肝损伤 ,减轻、延缓肝纤维化趋势 ,无不良反应。Objective: To observe the therapeutic effect of adjusted Buyang Huanwu decoction (ABHD) on fatty liver and explore its clinical application value in resisting liver fibrosis. Methods:Eighty nine cases with fatty liver were randomly divided into 2 groups: the treatment group (n=59) treated with ABHD and the control group (n=30) treated with Danshen tablet and Ethyl Polyenoate soft capsule. The clinical effect, changes of serum HA (hyaluronic acid), globin, ALT and B ultrasound were observed before and after the treatment. Results: After the treatment, the biochemical indices of the two groups were both decreased. There was significant difference between the two groups (P< 0.01 ). The effective rate of the treatment group was 96.4% and that of the control group was 76.7%, with significant difference between them (P< 0.01 ). Conclusion: ABHD can significantly ameliorate the liver injury of fatty liver, alleviate and delay the trend of liver fibrosis with no bad effection.

关 键 词：脂肪肝 补阳还五汤 丹参片 多烯康 肝纤维化 

分 类 号：R575.5[医药卫生—消化系统]