颅底肿瘤的X刀治疗  

X-knife for Tumors of Skull Base

作　　者：李赞[1] 吴湘玮[1] 包荣华[1] 张九堂[1] 瞿吉保[1] 何正文[1] 

机构地区：[1]湖南省肿瘤医院,湖南长沙410006

出　　处：《肿瘤学杂志》2003年第2期93-95,共3页Journal of Chinese Oncology

摘　　要：[目的]探讨颅底肿瘤的X刀治疗效果。[方法]1996年10月至1999年12月期间对93例(95个病灶)颅底肿瘤患者实施了X刀治疗。[结果]随访11个月～68个月,93例患者中81.72%X刀治疗后获得临床症状改善,2例患者于X刀治疗后6个月、12个月因脑水肿而行手术治疗;1例失明,6例死于复发或转移。影像学观察病灶全部消失18个,体积缩小35个,无明显变化38个,病灶增大4个,肿瘤控制率95.79%。[结论]对经过选择的颅底肿瘤实施X刀治疗,可以获得良好的局部肿瘤控制效果和较低的治疗并发症及后遗症。对诊断不明确的患者可采用立体定向穿刺活检确诊后再行X刀治疗。To explore the result of treatment for skull base tumors by X-knife.From Oct.1996to Dec.1999,93pa-tients with skull base tumors were treated by X-knife.After follow-up of11～68months,81.72%of patients revealed symptomatic improvement,2patients underwent reoperation at6and12months after X-knife treatment,1was ablepsia,6died of recurrence or metasta-sis.Of the95tumor lesions,18completely disappeared,35shrinked in volume,no changes in38and4tumors enlarged by CT/MR detection.[Conclusions]X-knife would provide a good treatment result for selected cases of skull base tumors with minor toxicity in majority of pa-tients.The patients with uncertain diagnosis should be comfirmed by stereotactic biopsy before X-knife treatment.

关 键 词：颅底肿瘤 X刀治疗 影像学 脑水肿 手术 立体定向放射治疗 

分 类 号：R739.41[医药卫生—肿瘤]