胃癌术前血浆缩醛磷脂与总胆固醇水平的比较分析  

The comparable study of the content of plasmalogen in plasma and total cholesterol before operation for gastric carcinoma

作　　者：杨红[1] 吕灿群[1] 

机构地区：[1]皖南医学院生物化学教研室

出　　处：《皖南医学院学报》2003年第1期8-9,共2页Journal of Wannan Medical College

基　　金：安徽省教委自然科学研究基金 (编号 97JL15 8)资助

摘　　要：目的　研究胃癌患者血浆缩醛磷脂含量的变化并与总胆固醇含量变化的相关性进行比较分析。方法　对临床确诊的 3 6例胃癌患者及 3 8例正常成人分别测定其血浆缩醛磷脂和总胆固醇的含量。结果　①胃癌患者血浆缩醛磷脂含量较正常人对照组明显增加 ,且差异有统计学意义 (P <0 .0 5 )。②胃癌患者血浆总胆固醇含量较正常人对照组亦明显增加 ,差异有统计学意义 (P <0 .0 5 )。③胃癌患者组中 (术前 ) ,血浆缩醛磷脂与总胆固醇呈正相关关系 (r =0 .82 ,且P <0 .0 0 1)。结论　在胃癌患者中 ,血浆缩醛磷脂含量显著增高 。Objective\ To study the changes of the content of plasmalogen (Plas) in plasma in patients with gastric carcinoma; and to analyse their correlation as compared with the changes of the content of totle cholesterol (TC) . Methords\ 36 patients with gastric malignant tumors confirmed clinically : The plasma content of Plas TC was determined and compared with those of normal control group. And the correlation was analysed. Results\ ①.The plasma Plas level of gastric carcinoma was significantly higher than that of normal control, P<0.05. ②The level of TC in plasma in gastric carcinoma was significantly higher than that of normal control group,P<0.05. ③In gastric carcinoma group:The relationship between Plas and TC had positive correlation (r=0.82,P<0.001). \ Conclusion\ In patients with gastric carcinoma,the content of plasmalogen in plasma increases significantly ,and has positive correlation with the increase of the content of TC.

关 键 词：胃癌 术前 血浆缩醛磷脂 总胆固醇 

分 类 号：R735.2[医药卫生—肿瘤]