白细胞、血小板动态变化与蛛网膜下腔出血后脑血管痉挛的关系  

Correlation of white blood cell and platelet counts' serial changes with symptomatic vasospasm after subarachnoid hemorrhage

作　　者：解旭东[1] 冀风云[1] 汪明慧[1] 王婷[1] 刘建辉[1] 王健[1] 

机构地区：[1]中国人民解放军252医院神经内科,保定071000

出　　处：《河南实用神经疾病杂志》2003年第2期15-17,共3页Henan Journal of Practical Nervous Diseases

摘　　要：目的研究蛛网膜下腔出血患者外周血白细胞及血小板动态变化,探讨其对蛛网膜下腔出血后脑血管痉挛的预测价值。方法 发病24h内的蛛网膜下腔出血病人共60例,其中男34例,女26例,平均56.1±12.8岁。根据是否发生脑血管痉挛患者分为两组:脑血管痉挛组74例,无脑血管痉挛组36例。Hunt-Hess临床分级:脑血管痉挛组Ⅱ级8例,Ⅲ级11例,Ⅳ级5例;无脑血管痉挛组Ⅰ级9例,Ⅱ级24例,Ⅲ级3例。采用全自动血细胞分析仪,对患者发病后ld及3d、7d、14d晨肘静脉血白细胞及血小板数量动态观察比较。结果 脑血管痉挛组患者发病后3d、7d、14d白细胞计数明显高于无脑血管痉挛组患者(P<0.01),两组发病后24h、3d、7d、14d血小板计数无统计学差异(P>0.05)。结论 蛛网膜下腔出血后脑血管痉挛患者外周血白细胞增加、外周血白细胞动态变化可作为预测脑血管痉挛发生的指征之一。Objective To study the correlation of white blood cell and platelet counts' serial changes with symptomatic vasospasm after sub-arachnoid hemorrhage. Methods Serial changes in white blood cell (WBC) and platelet counts were analyzed in 60 patients with aneurysmal sub-arachnoid hemorrhage (SAH) .Results The WBC counts during days 1,3,7,14 after the onset of SAH were significant higher in patients with than in patients without symptomatic vasospasm.Platelet counts during days 1,3,7,14 after SAH were no significantly different in patients with than in patients without symptomatic vasospasm. Conclusion Monitoring of WBC counts may provide an indicator of the occurrence of symptomatic vasospasm.

关 键 词：蛛网膜下腔出血 外周血 白细胞 血小板动态变化 脑血管痉挛 

分 类 号：R743.35[医药卫生—神经病学与精神病学]