家族性与散发性精神分裂症临床特点比较研究  

A comparative study in the clinical features between familial and sporadic schizophrenia.

作　　者：李成林 邓晓瑛[2] 

机构地区：[1]成都市精神病院,610091 [2]成都市结核病防治院,四川成都610016

出　　处：《中国民康医学》2003年第2期82-84,共3页Medical Journal of Chinese People’s Health

摘　　要：目的 :比较家族性与散发性精神分裂症临床特点之异同 ,为临床诊治及精神分裂症亚型的划分提供参考。方法 :采用自制问卷、SANS和SAPS量表、PSE量表、GAS和GAF量表对 4 0例家族性和 4 0例散发性精神分裂症进行检查评定 ,将结果进行 χ2 检验、t检验。结果 :二组起病形式 ,一些临床症状有显著性差异 ;发病年龄、住院次数、复发次数、诱发因素、临床综合征、疗效及社会功能无显著性差异。结论 :家族性精神分裂症与散发性精神分裂症临床特征有一些不同 ,家族性精神分裂症以急性和亚急性起病、临床表现以妄想和核心症状群多见 ;而散发性精神分裂症起病缓慢 ,临床表现以社会退缩 ,疏懒 ,行为、情感言语障碍多见。Objective:To compare clinical features on difference between familial and sporadic schizophrenia, so as to provide reference to clinical diagnosis?treatment and the subtype definition of schizophrenia. Method: 40 familial schizophrenia and 40 sporadic schizophrenia were investigated, using self-designed questionnaire?SANS?SAPS?PSE?GAS?GAF scale. Data were analysed by SPSS 10.0 (Statistical Package for the Social Science) on computer. Results: There are obvious differences on the form of onset and some symptoms between the two groups. No differences were found in age of onset?frequency of being in hospital and recurrence?induced factor?clinic syndrome?treatment effect and social function between the two groups. Conclusion: There are some difference on the chinical feature between familial and sporadic schizophrenia. Acute onset?delusion and symptoms of nucleus are the main clinical features of familial schizophrenia. most of sporadic schizophrenia have chronic onset and severe impairment of social function?laziness?disorder of behavior?mood and speech.

关 键 词：临床特点 精神分裂症 家族史 

分 类 号：R749.3[医药卫生—神经病学与精神病学]