福松对慢性功能性便秘肛门直肠运动的作用及疗效观察  

The Effect of Rorlax on Anorectal Motility and Therapy in Patients with Chronic Functional Constipation

作　　者：刘诗[1] 谢小平[1] 候晓华[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院,武汉430022

出　　处：《临床消化病杂志》2003年第2期71-72,共2页Chinese Journal of Clinical Gastroenterology

摘　　要：目的:了解福松对慢性功能性便秘患者的治疗效果及对肛门直肠运动的作用。方法:将40例慢性功能性便秘患者随机分为福松组和乳果糖组。治疗两周,观察疗效及副作用。采用水灌注式测压系统检测10例慢性功能性便秘患者福松治疗前后肛门直肠运动功能。结果:福松和乳果糖治疗后排便次数明显增加,大便性状得到改善,80％左右患者排便困难缓解,70％患者排便质量改善,无明显副作用。福松治疗前后慢性功能性便秘患者肛门直肠动力和感觉无明显变化。结论:福松是治疗慢性功能性便秘的有效药物,对慢性功能性便秘患者肛门直肠运动功能无作用。Purpose To assess the therapeutic effectiveness fo forlax and the effect of forlax on anorectal motility in patients with chronic functional constipation. Methods: 40 patients suffering from chronic functional constipation were randomly allocated to receive either forlax or lactulose for 2 weeks, the therapeutic effectiveness and side effect of drugs were evaluated. Anorectal motility was investigted by wster-perfused manometric system in 10 patients treated with forlax. Results: The bowel frequency was significantly increased and the hard pellety stools were changed into soft ro thin stools in patients treated with either forlax or lactulose, the straining and the quality at defecation were obviously improved in about 80% and 70% patients treated with the drugs. Anorectal motility and sensation did not differ in patients before and after treatment with forlax. Conclusion; Forlax is and effective ding to treat chronic functional constipation, has no effect on anorectal motility in patients with chronic constipation.

关 键 词：疗效 慢性功能性便秘 福松 肛门直肠运动 治疗 

分 类 号：R574.62[医药卫生—消化系统]