妇科晚期恶性肿瘤的介入治疗  

Interventional therapy of malignant and advanced gynecologic cancer

作　　者：林浩东[1] 杜临安[1] 伏树奇[1] 李章钧[1] 张德志[1] 张秀泽[1] 

机构地区：[1]安徽医科大学第一附属医院放射科,合肥230022

出　　处：《安徽医科大学学报》2003年第1期56-58,共3页Acta Universitatis Medicinalis Anhui

摘　　要：目的　探讨妇科晚期恶性肿瘤介入治疗的临床价值。方法　 1 9例患者中宫颈癌 1 4例 ,子宫内膜癌 4例 ,卵巢癌 1例 ;全部病例均采用经髂内动脉或子宫动脉选择性化疗药物灌注和栓塞 ,其中单纯灌注化疗 1 2例 ,灌注化疗加栓塞 7例 ,1 6例治疗后Ⅱ期手术。结果　 1 9例患者行 2 0次介入治疗。其中 1 6例治疗后行Ⅱ期手术 ,术中见肿瘤缩小 ,中心坏死 ,肿块易剥离 ,术中出血明显减少。 1例 2次介入治疗 ,2例为手术后复发再行介入治疗。 3例单纯介入治疗而未手术者 ,治疗后复查CT或B超显示肿瘤缩小 ,中心密度减低。随访期 2～ 2 6个月 ,全部病例均存活 ,其中 8例存活 1年以上。无严重并发症发生。结论　介入治疗可为晚期妇科恶性肿瘤Ⅱ期手术创造条件 ,能提高生存率 。Objective To evaluate the clinial value of interventional therapy in patients with malignant and advanced gynecologic cancer. Methods In this study,19 cases of gynecologic cancer(including 14 carcinoma of cervix and 4 carcinoma of endometrium and 1 carcinoma of ovary) were treated with interventional management through internal iliac or uterine artery,among which 12 cases were treated with simple perfusion of chemical drugs and the others were treated with both perfusion and emblization. Operation was performed after interventional treatment in 16 cases. Results Twenty times of interventional treatment were perfomed on 19 patients,including 16 cases with secondary operation and 1 case with second interventional treatment and 2 cases with cancer recurrence after operation. Tumor shringe,central necrosis and the decrease of the amount of intraoperative hemorhage were found in all 16 surgical patients.All patients were alive now and 8 had survived for 1 year above. No serious complications was found in this group. Conclusion This technique is effective in treating malignant and advanced gynecologic cancer. It can improve the condition of patients for further operation and enhance the survival rate.

关 键 词：妇科晚期恶性肿瘤 介入治疗 宫颈癌 子宫内膜癌 卵巢癌 

分 类 号：R737.3[医药卫生—肿瘤] R730.55[医药卫生—临床医学]