放射治疗对肿瘤患者免疫功能的影响  

Effect of Radiotherapy on Immunity Function of Cancer Patients Receiving Radiotherapy

作　　者：李新莉[1] 朱圣陶[1] 徐久宏[2] 

机构地区：[1]苏州大学放射医学与公共卫生学院营养卫生教研室 [2]苏州大学附属第一医院放疗科,苏州215007

出　　处：《苏州大学学报（医学版）》2003年第2期190-192,共3页Suzhou University Journal of Medical Science

摘　　要：目的　观察放疗对肿瘤放疗患者免疫功能的影响。方法　采用APAAP法 (碱性磷酸酶抗碱性磷酸酶桥联酶标法 )检测细胞免疫功能 ;透影比浊法检测体液免疫功能。结果　放疗前、后 ,肿瘤患者的细胞免疫功能均低于正常对照组 ,放疗后 ,各检测指标进一步下降 ,且放疗前、后的差别具有统计学意义。体液免流功能指标 ,鼻咽癌患者表现为IgG升高 ,IgA、IgM下降 ,且IgG、IgA的变化具有统计学意义 ,而乳腺癌 ,放疗后IgA、IgM的下降具有统计学意义。Objective In order to observe the effect of radiotherapy on immunity function of cancer patients receiving radiotherapy. Methods Cellular immunity is determined by APAAP;Humoral immunity is determined by transmission methold. Results The items of cellular immunity is lower than the control after radiotherapy,These items decrease continuely,The difference between before and after radiotherapy has statistic significance.Of all Humoral immunity items,IgA?IgM decreased after radiotherapy and the difference has statistic significance. Conclusions Radiotherapy can damage patients' immunity function.

关 键 词：肿瘤 放射疗法 免疫功能 影响 APAAP法 细胞免疫功能 透影比浊法 

分 类 号：R730.55[医药卫生—肿瘤]