文拉法辛治疗儿童广泛性焦虑症的研究  

A study of venlafaxine in the treatment of generalized anxiety in childbood

作　　者：石志强[1] 任泽华[1] 王惠兰[1] 

机构地区：[1]山东滨州市人民医院精神卫生中心,256610

出　　处：《临床精神医学杂志》2003年第2期84-85,共2页Journal of Clinical Psychiatry

摘　　要：目的 :评价文拉法辛治疗儿童广泛性焦虑症的临床疗效和不良反应。　方法 :对 76例符合中国精神障碍分类与诊断标准第 3版诊断标准的儿童广泛性焦虑症患者 ,应用文拉法辛及阿普唑仑各 38例进行对照治疗。疗程 8周。采用汉密尔顿焦虑量表 (HAMA) ,临床疗效总评量表 (CGI) ,副反应量表 (TESS)评定疗效及不良反应。　结果 :两种药物的疗效相仿。对精神性焦虑文拉法辛优于阿普唑仑。文拉法辛不良反应少而轻。　结论 :文拉法辛是治疗儿童广泛性焦虑症安全有效药物。Objective:To study the efficacy and side effects of venlafaxine in the treatment of generalized anxiety in childhood. Method:76 patients were treated with venlafaxine and alprazolam respectively.All of them were observed for 8 weeks.The efficacy were assessed by HAMA,CGI and the side effects were assessed by TESS. Results:Both drugs showed similar effecacy in the treatment of generalized anxiety in childhood but venlafaxine was better than alprozolam in the treatment of psychic anxiety patients.Venlafaxine had less and slighter side effects. Conclusion:Venlafaxine is a safe and efficient drug in the treatment of generalized anxiety in childhood.

关 键 词：儿童 广泛性焦虑症 文拉法辛 阿普唑仑 临床疗效 不良反应 

分 类 号：R749.94[医药卫生—神经病学与精神病学]