肾缺血再灌注损伤中CD11a及髓过氧化酶的变化  

Change of CD11a and myeloperoxidase content during rat renal ischemia-reperfusion injury

作　　者：洪伟[1] 王禾[1] 石炳毅[2] 沈瑞雄[1] 柏宏伟[2] 李州利[2] 周文强[2] 

机构地区：[1]第四军医大学西京医院泌尿外科,陕西西安710033 [2]解放军309医院泌尿外科,北京100091

出　　处：《第四军医大学学报》2003年第8期764-765,共2页Journal of the Fourth Military Medical University

摘　　要：AIM: To observe the effects of continuous epidural block on nitric oxide level in plasma of the pregnancy induced hypertension patients. METHODS: Twenty tow female patients ASA class 1 2, scheduled for lective gynecological surgery served as non pregnancy group. Twenty tow normal late stage gravidas as pregnancy group and twenty tow severe pregnancy induced by pertepsion (PIH) gravidas as PIH group. The intarvenous blood samples were taken immediately before continuous epidural block and 15 min following continuous epidural block before incision. It quantiated the concentration of nitric oxide in plasma by measuring the metalolic production of nitric oxidemitrite and nitrate. RESULTS: Before continuous epidural blcok, nitmic oxide level in the plasma decreased significantly in non pregnancy group and PIH group compared with that in pregnancy group ( P <0 05). Nitric oxide level in plasma increased significantly after continuous epidural block in all three group ( P <0 05 or 0 01), CONCLUSION: Continuous epidural block can improve plasma the nitric oxide level in plasma of the patient with pregnancy induced hypertension indicating to produce therapeutic effect on pregnancy induced hypertension.AIM: To observe the effects of continuous epidural block on nitric oxide level in plasma of the pregnancy induced hypertension patients. METHODS: Twenty tow female patients ASA class 1 2, scheduled for lective gynecological surgery served as non pregnancy group. Twenty tow normal late stage gravidas as pregnancy group and twenty tow severe pregnancy induced by pertepsion (PIH) gravidas as PIH group. The intarvenous blood samples were taken immediately before continuous epidural block and 15 min following continuous epidural block before incision. It quantiated the concentration of nitric oxide in plasma by measuring the metalolic production of nitric oxidemitrite and nitrate. RESULTS: Before continuous epidural blcok, nitmic oxide level in the plasma decreased significantly in non pregnancy group and PIH group compared with that in pregnancy group ( P <0 05). Nitric oxide level in plasma increased significantly after continuous epidural block in all three group ( P <0 05 or 0 01), CONCLUSION: Continuous epidural block can improve plasma the nitric oxide level in plasma of the patient with pregnancy induced hypertension indicating to produce therapeutic effect on pregnancy induced hypertension.

关 键 词：淋巴细胞 功能相关 抗原-1 CD11A 髓 过氧化酶 肾 缺血再灌注 损伤 

分 类 号：R363[医药卫生—病理学]