阿尔茨海默病和血管性痴呆的精神行为症状  

Investigation on psychiatric and behavioral disturbances in Alzheimer's disease and vascular dementia

作　　者：贾建平[1] 贾健民 楚长彪[1] 徐敏[1] 周卫东[1] 

机构地区：[1]首都医科大学宣武医院神经科,北京100053 [2]河北省邯郸市第一人民医院,河北邯郸056002

出　　处：《中风与神经疾病杂志》2003年第2期113-116,共4页Journal of Apoplexy and Nervous Diseases

摘　　要：目的　探讨阿尔茨海默病 ( Alzheimer's disease,AD)和血管性痴呆 ( vascular dementia,VD)患者的精神行为症状特点及对早期诊断的价值。方法　对 80例 AD和 72例 VD的精神行为症状进行分类、比较和分析。结果　 VD患者焦虑 ( P=0 .0 0 2 4)和抑郁 ( P=0 .0 0 5 9)的发生率显著高于 AD患者 ,AD患者则以无目的闲逛 ( P=0 .0 0 18)明显多见 ;而情感失控和情绪不稳的发生率在两组痴呆患者中无明显差异。结论　 AD和 VD患者的精神行为改变各有其不同特点 ,这对二者的早期诊断和鉴别诊断有一定帮助。Objective To investigate psychiatric and behavioral differences between Alzheimer's disease (AD)and vascular dementia(VD)and to explore how these differences can be used to differentiate AD and VD in their early stage.Methods Psychiatric and behavioral disturbances in 80 cases of AD and 72 cases of VD were classified, compared and analyzed. Results Patients with VD showed significantly more anxiety and depression but less wanderings than those in AD patients, and no significant between-group differences were found in the prevalence of emotional lability. Conclusion There are psychiatric and behavioral differences between Alzheimer's disease and vascular dementia in their early stage, which is of some help for the differential diagnosis.

关 键 词：阿尔茨海默病 血管性痴呆 精神行为症状 早期诊断 

分 类 号：R749.16[医药卫生—神经病学与精神病学]