S-腺苷甲硫氨酸的稳定性及其稳定性盐  

Stability and Stable Salts of S-adenosylmethionine

作　　者：申丽[1] 李东阳[2] 姜涌明[1] 袁中一[2] 

机构地区：[1]扬州大学生物科学与技术学院,扬州225009 [2]中国科学院上海生命科学研究院生物化学和细胞生物学研究所,上海200031

出　　处：《药物生物技术》2003年第2期125-128,共4页Pharmaceutical Biotechnology

摘　　要：S -腺苷甲硫氨酸是生物体内重要的中间代谢物质 ,参与多种生化反应 ,具有广泛和多样的治疗作用 ,但其内在的不稳定性在很大程度上限制了它在临床上的应用。文章主要介绍了S -腺苷甲硫氨酸的失活机理。S-adenosyl-L-methionine is an important m etabolic intermediate in org anism, which is involved in many biochemical reactions. Its therapeuctic usage c ould be extensive and varied, however its intrinsic instability limit its clini cal application to a large extent. This paper introduce its degradation mechanis m and stabilized theory, also refer to the novel stable salts of S-adenosyl -L-methionine with polyanions.

关 键 词：S-腺苷甲硫氨酸 稳定性 稳定性盐 失活机理 

分 类 号：Q517[生物学—生物化学]