决明子中蒽醌类化学成分及其生物活性研究进展  

Progress in studies of active coustituents of anthraquinones and their biological activities from Semen Cassiae

作　　者：陈秋东[1] 徐蓉[2] 徐志南[1] 岑沛霖[1] 

机构地区：[1]浙江大学生物工程研究所 [2]杭州中美华东制药有限公司,浙江杭州310013

出　　处：《中国现代应用药学》2003年第2期120-124,共5页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的　研究决明子中蒽醌类物质的构效关系 ,以推动新药开发。方法　综述了近几年来中药决明子中蒽醌类活性成分的提取与分离、定性与定量分析、化学成分、生物活性及其机理 ,以及利用生物技术培养决明生产蒽醌类物质等研究状况。结果与结论　决明子中含丰富的蒽醌类物质 ,可以筛选出高效的先导物用于开发抗癌、抗菌。OBJECTIVE To promote the deeply research on the relationship of pharmacology and structure of anthraquinone from Chinese herbal medicine semen cassiae . METHOD It made a textual review on anthraquinones from semen cassiae in extraction,indentification,determination,chemical structure, bioactivity, and cultivate production by biotechnology.RESULTS & CONCLUSION Many anthraquinones from semen cassiae were studied, which is valuable in the explortation of new nature drugs of anti cancer, anti germ, or eyes brighting, etc..

关 键 词：决明子 蒽醌类化学成分 提取方法 分离方法 定量分析 化学成分 生物工程技术 生物活性 

分 类 号：R282.71[医药卫生—中药学] R284[医药卫生—中医学]