恩施市沙地区土家族先天畸形遗传病及主要地方病调查报告  

Investigation of Genetic Epidemiology in Shadi Region of Enshi of Hubei

作　　者：吴怀安[1] 曾宪昌[1] 任波[1] 陈卫国[1] 雷道雄[1] 王春[1] 薜英 薜贵乐 闵心诚 农德祥 

机构地区：[1]湖北医学院 [2]恩施市卫生局

出　　处：《湖北医学院学报》1992年第1期53-57,共5页

基　　金：湖北医学院科研处资助;恩施市卫生局资助

摘　　要：通过调查湖北恩施沙地区15853人,发现各类疾病患者2832人,患病率为17.86％。分析确认为遗传性疾病者4.49％。近亲结婚率为12.5％。研究结果表明。沙地区地球化学异常,当地人群遗传负荷高,文化素质低及缺医少药是该地区多种疾病高发生率的主要原因。2832 hereditary malformations and main endemic diseases were found in 15853 population of Sha- di region of Enshi,Hubei,China,with the prevalence rate of 17.86％.Hereditary malformation cas- es accounted for 4.4％(712/15853)of all cases.The inbreeding rat was 12.5％(71/568).The main endemic diseases were fluarine,cadmium,salemium poisoning and endemic goiter,cretinism. This investigation led to the conclusion that the abnormal earth-chemistry of Shadi region,the high ge- netic load and lower culture level,short of medicament were chief reasons with high incidence rate of Shadi region.

关 键 词：遗传性疾病 流行病学 调查 

分 类 号：R596.01[医药卫生—内科学]