蛋白质组及其研究技术在环境卫生学领域的应用  

Application of Proteomic Techniques in the Field of Environmental Health

作　　者：杨玉花[1] 袭著革[1] 晁福寰[1] 

机构地区：[1]军事医学科学院卫生学环境医学研究所,天津300050

出　　处：《环境与健康杂志》2003年第3期190-192,共3页Journal of Environment and Health

摘　　要：对研究蛋白质组的意义、蛋白质组的定义和技术体系作了简要介绍。在后基因组时代,蛋白质组学的研究越来越受到关注,因为,基因表达产物———蛋白质的变化,是导致生命功能失常的直接因素;蛋白质组是指一种细胞、组织或有机体所表达的全部蛋白质;蛋白质组研究技术主要包括双向电泳、质谱和生物信息学。还对近年来国内外在环境卫生学方面对蛋白质组技术的应用作了综述。The meaning of proteome research,definition and technique system of proteome are summarized in this article.In the post-genome age,research on proteomics has become more and more important,because changes in proteins which are expressed by genes are the direct causes of life function disorders.Proteome is the entire complement of proteins expressed by a kind of cell,tissue or organism.Proteomic techniques mainly include two-dimensional electrophoresis,mass spectrometry and bioinformatics.In addition,the application of proteome techniques published home and abroad in the field of environmental health in recent years has also reviewed in this paper.

关 键 词：蛋白质组 蛋白质组学 双向电泳 质谱 

分 类 号：Q51[生物学—生物化学] R12[医药卫生—环境卫生学]