经口内镜缝合治疗胃食管反流病的初步研究  

STUDY ON TRANSORAL ENDOSCOPIC SUTURING FOR TREATMENT OF GASTRESOPHAGEAL REFLUX DISEASE

作　　者：缪林[1] 范志宁[1] 季国忠[1] 吴萍[1] 文卫[1] 蒋国斌[1] 章爱春[1] 李农[1] 刘政[1] 黄光明[1] 

机构地区：[1]南京医科大学第二附属医院内镜中心,南京210011

出　　处：《中国内镜杂志》2003年第5期39-41,共3页China Journal of Endoscopy

基　　金：江苏省科技厅社会发展基金(BS2 0 02 32 8)

摘　　要：目的 :初步观察经口内镜缝合治疗胃食管反流病 (GERD)疗效及并发症。方法 :对经胃镜、食管PH检测等确诊的 1 0例胃食管反流病患者在PENTAXEPM - 330 0电子胃镜下采用美国BARD缝合器缝合胃胃底 ,缝合部位选择齿状线下 1cm ,两针间距 1 .5cm ,两结间距 2 .0cm。观察术前及术后 1月症状积分及术后并发症。结果 :1 0例患者共缝合 2 4针 ,1 2个结 ;平均手术时间 30min ,总有效率 90 % ,完全缓解 60 % ,部分缓解30 % ,无效 1 0 %。结论 :经口内镜缝合治疗胃食管反流病近期疗效肯定 ,并发症少 ,远期疗效、并发症有待进一步研究。Objective:To observe the effect and complication for transoral endoscopic suturing for treatment of gastresophageal reflux disease(GERD). Methods: Ten patients with GERD treated with an endoscopic suturing device,which were made in the U.S.Patients underwent endoscopy, 24-hour pH monitoring, and symptom severity scoring before and after the procedure. Adverse procedural events were recorded. Locus of endoscopic suturing was located in one centimeter below dentation line.Results: Ten patients underwent twelve endoscopic gastroplasty procedures. Mean procedures time was thirty minutes .Heartburn scoring were 21 and 8 before and after the procedure. Regurgitation scoring were 17 and 7 before and after the procedure .Total utility rate was 90%,complete remission rate was 60%. Partial remission rate was 30%, inefficiency rate was 10%.Complications were bleeding and chest pain. Conclusion:There were affirmed effect in the near future and few complication on transoral endoscopic suturing for treatment of GERD. Long-term effect and complication would be studied in the future.

关 键 词：内镜缝合 胃食管反流病 GERD RARD缝合器 PH检测 

分 类 号：R57[医药卫生—消化系统]