腹泻病儿血中维生素A、锌、铜含量变化的研究  

Studies on Vitamin A, Zinc, Copper Concentration in Blood of Children with Diarrhoea

作　　者：阎怀成[1] 徐青梅[1] 张淑敏[1] 潘丽梅[1] 陈学存[1] 李飞卫 王全平 胡俊[1] 

机构地区：[1]中国预防医学科学院营养与食品卫生研究所,北京100050 [2]河南省新乡市卫生防疫站

出　　处：《基础医学与临床》1992年第1期23-25,共3页Basic and Clinical Medicine

摘　　要：1990年6月至10月在新乡市医院选择新入院6月至5岁腹泻病儿80例和在门诊选择同年龄健康儿童21例,静脉取血测定其血中维生素A、锌、铜的含量及免疫球蛋白的含量。研究结果表明腹泻病儿血中维生素A(26.4±14.6μg/dl)明显低于健康儿童(54.9±17.0μg/dl)。有统计学上显著性差异(P<0.01),血清锌含量和铜/锌比值腹泻病儿为95.0±46.0μg/dl和1.51±0.44,健康儿童为127.4±34.3μg/dl和1.02±0.40,均有显著性差异(P<0.01),血清铜含量两组儿童无差异。免疫球蛋白IgA和IgG两组儿童无差异,而IgM的含量腹泻病儿明显高于健康儿童,有显著性差异。本文研究结果说明维生素A的不足或缺乏会增加腹泻病发生的危险性,若改善儿童的维生素A的营养状况可能会减少腹泻病发生的机会。Eighty diarrhoeal and twenty-one healthy children were selected for experimental and control groups from Xin Xiang hospital of He Nan Province.Their age was six months to five years.The mean serum Vitamin A, zinc and copper concentrations were 26.4±14.6; 95.0±46.0 and 132.2±45. 1ug/dl respectively in the diarrhoeal group; and 54.9±17.0, 127.4±34.3, 123.5±46.7μg/dl respectively in the healthy group. Serum Vitamin A and zinc concentrations in diarrhoeal group were lower than that of control group with significant difference ( P<0.01 ) .The serum Vitamin A and zinc contents below 30μg/dl and 70μg/dl were 63.7 and 16.2 percent in diarrhoeal group and all the healthy children were above 30μg/dl and 70μg/dl respectively .Serum IgM in diarrhoeal children was significantly higher than that of healthly children(P<0.05). No difference of serum copper, IgA and IgG was found between two groups.The results showed that improvement of Vitamin A nutritional status may decrease the incidence of diarrhoea in children.

关 键 词：腹泻 维生素A 锌 铜 儿童 

分 类 号：R723.11[医药卫生—儿科]