学龄前期儿童骨骼畸形的临床综合研究与分析  

The Clinical Comprehensive Study and Analysis of Preschool Children Bone Deformity.

作　　者：龚群[1] 刘锋[1] 周惠琴 张建萍[1] 沈时霖[3] 

机构地区：[1]上海市儿童医院儿童保健所,上海200040 [2]上海市静安区妇幼保健所,上海200042 [3]上海市第一人民医院,上海200080

出　　处：《中国儿童保健杂志》2003年第3期172-173,179,共3页Chinese Journal of Child Health Care

摘　　要：【目的】　研究有骨骼畸形的小儿体内骨代谢状况。　【方法】　采用病例对照研究方法 ,通过临床问卷调查及骨碱性磷酸酶 (BALP)检测 ,对阳性患儿进一步作血生化及腕部X线摄片检查 ,并与对照组分析比较。　【结果】　 12 6例 4～ 6岁骨骼有畸形的小儿中BALP测定阳性率为 2 4.60 % ,诊断为儿童期佝偻病 ,经血钙、血磷、血碱性磷酸酶及X线检查 ,并与对照组比较 ,差异有显著意义 (P <0 .0 5 )。To study the state of bone metabolism in children with skeletal deformity . With cases contrast, clinical questionnaire, and bone alkaline phosphatase (BALP) were tested. Then blood biochemistry investigation and wrist X ray examination were taken in the patients with positive reaction, the results were analyzed with the method of group contrast. BALP inspection had been applied to 126 bone deformity children of 4～6 years old, 24.60% had positive reaction, diagnosed as childhood rickets. Compared with the contrast group,the result of the blood calcium, phosphous,alkaline phosphatase and X ray inspection in rickets, had significant differences ( P <0.05).[Conclusions] The diagnosis and prevention of preschool children rickets must be taken the matter seriously.

关 键 词：儿童期佝偻病 骨骼畸形 临床研究 

分 类 号：R179[医药卫生—妇幼卫生保健]