双功能化合物—二氯荧光素二丙烯酸酯的合成与生物活性  

Studies on preparation,biological activity of 2,7-dichloro -3,6-acrylate fluorescin ester with di-function

作　　者：唐慧安[1] 王志会 赵恺寅[1] 王流芳[3] 张培琰 杨汝栋[3] 

机构地区：[1]天水师院化学系,甘肃天水741001 [2]浙江纳爱斯化工股份有限公司 [3]兰州大学化学化工学院,甘肃兰州730000

出　　处：《化学研究与应用》2003年第3期419-420,共2页Chemical Research and Application

摘　　要：In this paper 2,7Dichloro3,6Acrylate Fluorescin Ester has been prepared and characterized by elementary analysis,IR,UV,1HNMR,Flourensence spectra.Afterwards,its antitumor activity was tested.The results showed that it has good flourensence and antitumor activity and it is a prospective antitumor agent.Then,use it to pigmentate broad bean farian.The results show that it has good determination function for broad bean cells vitality.So it is a selective determination agent for broad bean cellIn this paper 2,7Dichloro3,6Acrylate Fluorescin Ester has been prepared and characterized by elementary analysis,IR,UV,1HNMR,Flourensence spectra.Afterwards,its antitumor activity was tested.The results showed that it has good flourensence and antitumor activity and it is a prospective antitumor agent.Then,use it to pigmentate broad bean farian.The results show that it has good determination function for broad bean cells vitality.So it is a selective determination agent for broad bean cell vitality

关 键 词：双功能化合物 二氯荧光素二丙烯酸酯 合成 生物活性 抗肿瘤活性 蚕豆 花粉细胞 生活力 检测 荧光素 

分 类 号：R979.1[医药卫生—药品] R914.5[医药卫生—药学]