上皮性卵巢癌危险因素的病例—对照研究  

Case-control study on risk factors of epithelial ovarian cancer

作　　者：苗青[1] 孔北华[2] 胡平[3] 束怀符[3] 

机构地区：[1]济南铁路中心医院妇产科 [2]山东大学齐鲁医院妇产科 [3]山东大学公共卫生学院统计学教研室

出　　处：《山东大学学报（医学版）》2003年第2期168-170,174,共4页Journal of Shandong University:Health Sciences

摘　　要：目的:调查卵巢癌发病的危险因素,为预防卵巢癌的发生提供依据。方法:选择山东省19所地市以上综合医院住院、病理确诊的307例上皮性卵巢癌患者为病例组,同期住院的非恶性肿瘤患者307例为对照组,采用1:1配对设计,作条件logistic回归分析。结果:受过教育、经济状况好、多食肉类、甜食及脂肪、大便不规律、便秘、接触有害物质、精神抑郁、焦虑、精神紧张、性格急躁、精神创伤是卵巢癌发病的危险因素。而文盲、多食蔬菜水果、性格温和是降低卵巢癌发病危险的因素。单因素logistic回归分析后建立的多因素回归方程为:Y=-1.2856S17+1.9743S18-1.5918S38+1.4828S40。结论:多种因素影响卵巢癌的发生发展过程。Objective:To estimate the risk factors of ovarian cancer and provide proof for pre-venting ovarian cancer.Methods:In a case-control1:1match study307patients with epithelial ovarian cancer were matched with307patients suffering from other diseases.The data were analyzed through conditional significant logistic regression.Results:The risk factors of ovarian cancer were acceptance of education,the high income,high meat,sweet food and fat consumption,irregular defecation,constipa-tion,touch with poisons,depression,anxiety,impatience,stress,and mental trauma,while other factors such as illiteracy,high vegetable and fruit assiumption,mild temper decreased the risk of ovarian can-cer.Con clu sion:The etiology of ovarian cancer is multifactorial and no evidence shows any single etio-logic factor for ovarian cancer.

关 键 词：卵巢肿瘤 危险因素 保护因素 病例-对照研究 

分 类 号：R73－31[医药卫生—肿瘤] R737.31[医药卫生—临床医学]