医用几丁糖治疗颞下颌关节不可复性盘前移位的临床研究  

Clinical Study on Chitosan in Curing Irreducible Anterior Disc Displacement of Tempormandibular Joint

作　　者：刘卫军[1] 唐昭[1] 王文斌 

机构地区：[1]暨南大学医学院口腔系,510632 [2]上海其胜生物材料技术研究所

出　　处：《华西口腔医学杂志》2003年第3期197-199,共3页West China Journal of Stomatology

摘　　要：目的　观察医用几丁糖关节腔内注射对颞下颌关节不可复性盘前移位的临床治疗效果。方法　将30例颞下颌关节不可复性盘前移位患者 ,按就诊序号半随机分为试验组和对照组。试验组患者用几丁糖 1 0ml关节上腔注射治疗 ,对照组患者用强的松龙悬液 1 2 5mg关节上腔注射。注射治疗后 1d、1 4d复诊 ,测量最大张口度。结果　注射后 1 4d ,试验组患者平均张口度恢复到 (36 73± 4 6 9)mm ,比注射前增加 1 1 73mm ;对照组患者平均张口度为 (2 8 5 3± 5 81 )mm ,比注射前增加 3 86mm。试验组张口度增加值明显大于对照组 (P <0 0 5 )。结论　医用几丁糖是一种有效的治疗颞下颌关节不可复性盘前移位的生物材料。Objective\ To evaluate the clinical efficacy of intra_articular injection with 2% chitosan as a treatment for irreducible anterior disc displacement of the TMJ.Methods\ Total 30 patients with irreducible anterior disc displacement were divided into two groups according to quasi_randomizaion. The patients in test group received intra_articular injection with 1 0 ml of 2% chitosan into upper cavities of the suffered joints,in control group with 12 5 mg of prednisolone. The patients were followed up at the 1st day and 14th day after injection and the maximal mouth opening was measured.Results\ The maximal mouth opening at 14th day was (36 73±4 69) mm in test group, with 11 73 mm increase from baseline; and (28 53±5 81) mm in control group, with 3 86 mm increase, respectively. The increase of maximal mouth opening in test group was significantly higher than that of control group (P<0 05).Conclusion\ Chitosan is an effective biomaterial in curing irreducible anterior disc displacement of TMJs.\;

关 键 词：几丁糖 治疗 颞下颌关节 不可复性盘前移位 临床研究 

分 类 号：R782[医药卫生—口腔医学]