子宫体癌术后行盆腔介入治疗30例临床探讨  

Postopertive interventional therapy for endometrial carcinoma in 30 cases

作　　者：巫岳鹏[1] 梅卓贤[1] 何科[1] 

机构地区：[1]广州中山大学附属第一医院妇科,广州510080

出　　处：《中国临床医学》2003年第3期304-305,共2页Chinese Journal of Clinical Medicine

摘　　要：目的:探讨较晚期子宫体癌手术后行盆腔区域性介入治疗价值。方法:选择30例子宫体癌Ic～Ⅲ期病例,分别行广泛全宫切除术和盆腔淋巴清扫术,术后依不同分期决定行盆腔介入治疗次数。子宫体癌Ic期介入3次,Ⅱ期介入4次,Ⅲ期介入5次。介入的方法采用Seldinger经股动脉穿刺插管技术,选择性地将Cobra导管插入股动脉,并将化疗药物Carbo600mg,5-FU.1500mg注入双侧髂内动脉,30d1次。结果:30例子宫体癌Ic-Ⅲ期患者手术后分别经过盆腔介入治疗3～5次,并追踪观察1～6年,全部未见复发倾向。结论:对于子宫体癌Ic～Ⅲ期患者,术后加用盆腔介入治疗,根据本组30例追踪1～6年结果,未见复发倾向,估计对临床及预后有治疗价值。Objective: To study the curative effect of pelvic segmental intervention therapy for advanced endometrial carcinoma. Methods: Thirty cases of stage Ic- Ⅲ endometrial carcinoma were selected after radical hysterectomy and pelvic lymphadenectomy. Frequency of postoperative intervention therapy were depended on different stages: 3 times for stage Ic, 4 times for stage Ⅱ, 5 times for stage Ⅲ. Intervention is taken by Seldinger's technique with femoral artery catheterization. The Cobra catheter was selectively insert-ed into the femoral artery though which Carbo. 600mg, 5 - Fu 1500mg were infused into bilateral internai iliac artery, once for 30 days. Results: Thirty patients with stage Ic - Ⅲ endometrial carcinoma received postoperative intervention therapy for 3 - 5 times and were followed up for 1 - 6 years. No recurrence was discovered. Conclusion: According to 1 - 6 years' follow - up for the 30 cases in the group, the adjuvant postoperative pelvic intervention therapy was estimated positive in prognosis for patients suspected or confirmed with pelvic metastases intraoperatively or postoperatively.

关 键 词：子宫体癌 术后 盆腔区域性介入治疗 大剂量高效孕激素 三苯氧胺 比较 

分 类 号：R737.33[医药卫生—肿瘤]