蛛网膜下腔出血并发低钠血症的机制探讨(附49例分析)  

Study on the pathogenesis of hyponatremia following subarachnoid hemorrhage:A report of 49 cases

作　　者：余传庆[1] 王芳[1] 

机构地区：[1]安徽省淮南市第一人民医院神经内科,232007

出　　处：《蚌埠医学院学报》2003年第4期331-333,共3页Journal of Bengbu Medical College

摘　　要：目的 :探讨蛛网膜下腔出血 (SAH)患者并发低钠血症的发生率、临床特点及发生机制。方法 :回顾性分析 4 9例SAH并发低钠血症患者的临床、血清钠、CT及脑脊液检查资料。结果 :SAH中并发低钠血症的发生率占同期住院SAH患者的14 .80 % ,并发低钠血症者发生昏迷和病死率均高于对照组 (P <0 .0 5 ) ,低钠血症的发生与CT显示积血阳性、分布区域不同有关 ,尤其有脑梗死以脑表面有积血块和脑室内有出血者更易发生低钠血症。结论 :下丘脑 -垂体功能紊乱是引起SAH并发低钠血症的主要原因之一。Objective:To investigate the incidence,clinical features and pathogenesis of hyponatremia following subarachnoid hemorrhage(SAH).Methods:The clinical manifestations,serum natrium,CT data and cerebrospinal fluid tests of 49 cases of hyponatremia following SAH were analysed retrospectively.Results:The incidence of hyponatremia following SAH was 14.80%,and the occurrence of coma induced by hyponatremia and the mortality rate were higher than the controls( P <0.05).Hyponatremia was higly associated with the distribution of SAH on brain CT,and the patients with cerebral ischemia which was related to presence of blood in the surface of brain and collection of blood in the ventricles of the brain were more susceptible to hyponatremia.Conclusions:Dysfunction of hypothalamas pituitarium is one of the risk factors causing hyponatremia following SAH.

关 键 词：蛛网膜下腔出血 血钠过少 断层摄影术 X线计算机 

分 类 号：R743.35[医药卫生—神经病学与精神病学] R591.1[医药卫生—临床医学]