前额叶皮层在学习记忆中的作用  

The Role of Prefrontal Cortex in Learning and Memory: Studied with Transcranial Magnetic Stimulation

作　　者：王福顺[1] 冯鉴强[1] 郭瑞鲜[1] 王艳[1] 叶美红[1] Vincent Walsh 

机构地区：[1]中山大学中山医学院生理教研室 [2]英国牛津大学实验心理系

出　　处：《心理科学》2003年第3期468-470,共3页Journal of Psychological Science

基　　金：国家教委留学基金委资助

摘　　要：为了探讨前额叶皮层的功能,在被试进行联合搜索作业(conjunction search task)时,使用跨颅磁刺激干扰被试者右侧前额叶皮层的活动,观察被试者在学习前后的反应时间的变化。观察到磁刺激干扰前额叶的活动,明显地延长了被试者在学习前的反应时间,对学习之后的反应时间几乎没有变化。这说明右侧前额叶参与了记忆的编码,对记忆的提取没有作用。To probe into the function of the prefrontal cortex in learning and memory, the Transcranial Magnetic Stimulation (TMS) was applied over the right dorsolateral prefrontal cortex, while the subjects were doing conjunction tasks. It wao found that TMS increased the reaction time for the naive subjects but not for the non-naives. The right dorsolateral prefrontal cortex played an essential role in learning but not in memory;or the dorslateral prefrontal cortex played a role in memory encoding but not in retrieving.

关 键 词：前额叶皮层 学习记忆 作用 跨颅磁刺激 联合搜索作业 反应时间 记忆 跨颅磁刺激仪 

分 类 号：B842[哲学宗教—基础心理学]