国产消沫剂在青霉素发酵生产中的应用  

The Use of Chinese Defoaming Agent in the Production of Penicillin

作　　者：张春雷[1] 王晶[1] 

机构地区：[1]哈药集团制药总厂,150086

出　　处：《黑龙江医药》2003年第4期290-291,共2页Heilongjiang Medicine journal

摘　　要：目的:为了克服进口消沫剂成本较高,且路途遥远易造成供货不及时的缺点,在不影响生产水平的前提下用国产消沫剂同类产品代替进口消沫剂。方法:分别从溶解能力,消沫力和毒性几方面进行比较考察,最后用发酵罐试验。结果表明,国产消沫剂各项特性均与进口消沫剂相近,且不影响发酵水平。结论是国产消沫剂完全可以代替进口消沫剂用于青霉素发酵生产。Object:In order to overcome import defoaming agent have high cost and far away from China,it's difficult to supply goods in time.If we don't influence production,we take Chi- nese defoaming agent instead of import defoaming agent.Method:Compare them from solution, defoaming and toxicity.At last do zymosis can experiment.Result:Everything of Chinese defoam- ing agent are nearby import deoaming agent and bot influence the zymosis.Conclusion:During penicillin production,Chinese defoaming agent can instead of import defoaming agent.

关 键 词：消沫剂 青霉素 发酵生产 应用 

分 类 号：TQ465.1[化学工程—制药化工] TQ460.38