影响巨大垂体腺瘤手术疗效的几个问题探讨  

Study of Factors Affecting Curative Effects of Operation on Giant Pituitary Adenomas

作　　者：朱广廷[1] 刘晓震[1] 刘斌[1] 种衍军[1] 于春江[2] 

机构地区：[1]济宁市第一人民医院神经外科,山东济宁272111 [2]首都医科大学附属北京天坛医院神经外科,北京100050

出　　处：《中国临床神经外科杂志》2003年第3期169-171,共3页Chinese Journal of Clinical Neurosurgery

摘　　要：目的介绍56例巨大垂体腺瘤显微外科手术治疗经验,探讨影响手术疗效的几个问题。方法回顾性分析56例巨大垂体腺瘤病人的临床资料。据肿瘤的生长方向及部位分为四型,据此分别采用经蝶、经额下、额下经蝶、扩大经蝶、扩大额下硬膜外、额下-翼点等10种入路进行显微手术。重点介绍手术入路的选择及注意事项。结果56例巨大垂体腺瘤全切29例,近全切20例,大部分切除7例,无死亡。结论依据巨大垂体腺瘤的不同位置及生长方向选择适当的手术入路、掌握手术时机以及术后辅以放疗是提高手术疗效的重要手段。Objective To introduce the experience in treating huge pituitary adenomas and to explore the factors affecting the curative effect of microsurgery on giant pituitary adenomas.Methods The clinical data of56cases of huge pituitary adenomas were analyzed retrospectively.The tumors were classified as four types according to their location and extensive direction.The tumors were removed respectively by various operative approaches such as transsphenoidal,transsubfrontal,extended transsphenoidal,extended subfrontal extradual,subfrontal-transpterional ones and so on in56patients with huge pituitary adenomas.The choice of the surgical approach and the points for attention to the operation were introduced in the patients with huge pituitary adenomas.Results Of56patients with huge pituitary adenomas,29received total removal of the tumors,20subtotal and7greater part.No patients died.Conclusion Choosing the appropriate approach,operative opportunity and post-operation radiotherapy can improve prognosis in the patients with huge pituitary adenomas.

关 键 词：巨大垂体腺瘤 显微外科手术 疗效 

分 类 号：R736.4[医药卫生—肿瘤] R651.13[医药卫生—临床医学]