Two Novel Antifungal Saponins from Tibetan Herbal Medicine Clematis tangutica  

作　　者：Zhi Zhi DU Na ZHU Yue Mao SHEN 

机构地区：[1]Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650204

出　　处：《Chinese Chemical Letters》2003年第7期707-710,共4页中国化学快报(英文版)

基　　金：This work was supported by the Ministry of Science and Technology grant 2001-51;the National Natural Science Foundation of China(30070007),Natural Science Foundation of Yunnan Province(99B0017G).

摘　　要：Antifungal assay-guided isolation of the ethanol extract of the aerial parts of Clematis tangutica yielded two novel triterpene saponins. Their structures were determined to be 3-O-a-L-arabinopyranosyl hederagenin 28-O-a-L-rhamnopyranosyl ester (1) and 3-O-b-D- glucopyranosyl(14)-a-L-arabinopyranosyl hederagenin 28-O-a-L-rhamnopyranosyl ester (2) on the basis of spectral data and chemical reactions.Antifungal assay-guided isolation of the ethanol extract of the aerial parts of Clematis tangutica yielded two novel triterpene saponins. Their structures were determined to be 3-O-a-L-arabinopyranosyl hederagenin 28-O-a-L-rhamnopyranosyl ester (1) and 3-O-b-D- glucopyranosyl(14)-a-L-arabinopyranosyl hederagenin 28-O-a-L-rhamnopyranosyl ester (2) on the basis of spectral data and chemical reactions.

关 键 词：Clematis tangutica triterpene saponins HEDERAGENIN antifungal assay. 

分 类 号：TQ461[化学工程—制药化工]