HEDERAGENIN

作品数：8被引量：59H指数：5
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相关领域：医药卫生理学更多>>
相关作者：刘明明蔡琳玲范君婷陈雪晴尤蓉蓉更多>>
相关机构：东南大学安徽中医药大学南京中医药大学南京医科大学更多>>
相关期刊：《细胞与分子免疫学杂志》《Chinese Herbal Medicines》《中草药》《Journal of Life Sciences》更多>>
相关基金：国家自然科学基金江苏省药学会奥赛康临床药学研究基金更多>>
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Systems pharmacology dissection of action mechanisms for herbs in osteoporosis treatment被引量：6
《Chinese Herbal Medicines》2021年第3期313-331,共19页Ying Huai Wen-juan Zhang Wei Wang Kai Dang Shan-feng Jiang Dan-ming Li Meng Li Qiang Hao Zhi-ping Miao Yu Li Ai-rong Qian 
supported by the National Natural Science Foundation of China under No.81901917 and No.31570940;the key grant BKJ17J004 and the Key Research and Development Project of Shaanxi Province under No.2018SF-363;China’s Post-doctoral Science Fund under No.2017M623249;the Fundamental Research Funds for the Central Universities under No.3102017OQD050。
Objective:Osteoporosis has become the biggest cause of non-fatal health issue.Currently,the limitations of traditional anti-osteoporosis drugs such as long-term ill-effects and drug resistance,have raised concerns tow...
关键词：asperosaponinⅥ betulinic acid CALYCOSIN HEDERAGENIN LUTEOLIN drug discovery osteoporosis SYSTEMS 
常春藤皂苷元(hederagenin)通过抑制STAT3通路降低CaSki宫颈癌细胞增殖能力并促进其凋亡被引量：11
《细胞与分子免疫学杂志》2019年第2期140-145,共6页方丽文 刘明明 蔡琳玲 
目的探讨常春藤皂苷元(hederagenin)对宫颈癌细胞活性及凋亡的影响及机制。方法培养CaSki宫颈癌细胞,采用(0、 10、 20、 40、 80)μg/mL常春藤皂苷元处理,噻唑蓝(MTT)法测定细胞活性,确定其半数抑制剂量约40μg/mL。采用40μg/mL常春...
关键词：常春藤皂苷元(hederagenin) 宫颈癌 细胞凋亡 STAT3 CASKI细胞 
藏药印度獐牙菜化学成分研究被引量：10
《中草药》2017年第24期5112-5116,共5页陈雪晴 尤蓉蓉 何丹丹 黄长高 钱士辉 范君婷 鞠建明 
国家自然科学基金资助项目(31500278);江苏省药学会奥赛康临床药学研究基金(210303);南京医科大学药学院大学生创新训练计划项目(2017YXDC02)
目的研究藏药印度獐牙菜Swertia chirayita的化学成分。方法采用硅胶、MCI、Sephadex LH-20等色谱方法进行分离纯化,依据理化性质、波谱数据分析进行结构鉴定。结果从印度獐牙菜85%乙醇提取物的醋酸乙酯萃取部位分离并鉴定了12个化合物...
关键词：印度獐牙菜 酮 三萜 裂环烯醚萜 4-epi-hederagenin 当药苦酯苷 红白金花内酯 儿茶酚 丁香酸 
Study on Flavonoids and Triterpenoids Content of some Euphorbiaceae Plants被引量：1
《Journal of Life Sciences》2011年第2期100-107,共8页Laila Abdel-Ghany Refahy 
The Spurge family （Euphorbiaceae） is a large family of flowering plants. Two plant species of this family were collected from the Egyptian desert, extracted with methanol subjected to silica gel column chromatograph...
关键词：Euphorbiaeeae Euphorbia retusa Euphorbiaparalais FLAVONOIDS TRITERPENE HEDERAGENIN lupine. 
Septemloside III: A Nonasaccharide Saponin from the Bark of Kalopanax septemlobus (Thunb.) Koidz.被引量：2
《Chinese Chemical Letters》2005年第1期53-56,共4页JianYuanYIN QinMENG EnSiWANG 
A nonasaccharide saponin, new hederagenin saponin, had been isolated from the bark of Kalopanax septemlobus (Thunb.) Koidz., and its structure was elucidated by HRESI-MS, NMR experi- ments and chemical analyses as 3...
关键词：Kalopanax septemlobus (Thunb.) Koidz. hederagenin saponin septemloside. 
Two Novel Antifungal Saponins from Tibetan Herbal Medicine Clematis tangutica被引量：21
《Chinese Chemical Letters》2003年第7期707-710,共4页Zhi Zhi DU Na ZHU Yue Mao SHEN 
This work was supported by the Ministry of Science and Technology grant 2001-51;the National Natural Science Foundation of China(30070007),Natural Science Foundation of Yunnan Province(99B0017G).
Antifungal assay-guided isolation of the ethanol extract of the aerial parts of Clematis tangutica yielded two novel triterpene saponins. Their structures were determined to be 3-O-a-L-arabinopyranosyl hederagenin 28...
关键词：Clematis tangutica triterpene saponins HEDERAGENIN antifungal assay. 
Two New Triterpenoid Glycosides from Elsholtzia bodinieri Vant被引量：7
《Chinese Chemical Letters》2002年第3期253-255,共3页WeiMingZHU HongPingPE 等 
Two new triterpenoid glycosides, hederagenin-3-O-b-D-xylopyranoside (1), dodecandral 3-O-b-D-xylopyranoside(2), were isolated from Elsholtzia bodinieri Vant. The structures of 1 and 2 were established by spectroscopi...
关键词：Hederagenin xyloside Elsholtzia bodinieri Labiatae. 
Triterpenoid Saponins from Clematis tangutica被引量：1
《Chinese Chemical Letters》1999年第5期391-394,共4页Hui Min ZHONG Chang Xiang CHEN Xuan TIAN Yu Xin CfIUI Yao ZuCHEN(Department of Chemistry. State Key Laboratory of Applied Organic Chemistry.Lanzhou University. Lanzhou 73000Kunming Institute of Botany.The Academy of Sciences of China, Kunming 630204Dep 
Two new triterpenoid saponins, tanguticoside A and B were isolated from aerial part of Clematis tangutica. Their structures were elucidated as 3-O-beta-D-glucopyranosyl hederagenin 28 O-alpha-L-rhamnopyranosyl- (1-->4...
关键词：Clematis tangutica RANUNCULACEAE triterpenoid saponins HEDERAGENIN tanguticoside A and B 
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