醋酸去炎松在玻璃体切割术和黄斑水肿的临床应用研究进展  

Recent clinical application of triamcinolone acetonide in vitrectomy and macular edema

作　　者：王琳[1] 惠延年[1] 

机构地区：[1]第四军医大学西京医院眼科,全军服科研究所陕西西安710032

出　　处：《眼科新进展》2003年第4期296-298,共3页Recent Advances in Ophthalmology

摘　　要：去炎松是一种非水溶性的长效糖皮质激素,能强力抑制炎症。已被用作抗炎药防治实验性增生性玻璃体视网膜病变和眼内新生血管形成。新近在玻璃体切割术中将去炎松 注入玻璃体内,能增加玻璃体的可见度,提高手术操作的安全性,并抑制术后血-眼屏障的破坏。玻璃体内注射醋酸去炎松还用于治疗难治性糖尿病黄斑水肿,由于视网膜中央静脉阻塞或炎症引起的慢性黄斑水肿,以及渗出性年龄相关性黄斑变性。这是一种有希望的疗法,目前尚未发现不能控制的并发症。其长期效果和安全性还有待评价。Triamcinolone acetonide is a water-insoluble and long-standing corticcxsteroid which strongly inhibits inflammation. It has been used as a potent anti-inflammatory agent for experimental proliferative vitreoretinopathy and intraocular neovascularization. Recently the intraocular injection of triamcinolone during a vitrectomy improves the visibility of the vitreous and the safety of surgical procedures and also inhibits the postoperative breakdown of the blood-ocular barrier. Intravitreal injection of triamcinolone acetonide which has also been used for treatment of refractory diabetic macular edema, chronic macular edema due to central retinal vein occlusion or inflammation, and exudative age-related macular degeneration. It is a promising therapeutic method and no uncontrollable complications have been noted. The long-term efficacy and safety need to further assessment.

关 键 词：醋酸去炎松 玻璃体切割术 黄斑水肿 玻璃体内 注射 

分 类 号：R774[医药卫生—眼科]