应用冷循环集束电极射频治疗晚期肝癌的疗效观察  

Clinical Application of Cluster Electrode Radio-frequency Ablation in The Treatment of Advanced Liver Cancer

作　　者：杨宇[1] 王宏辉[1] 马东营[1] 王立平[1] 叶远树[1] 

机构地区：[1]哈尔滨医科大学附属第二医院,黑龙江哈尔滨150086

出　　处：《肿瘤学杂志》2003年第4期195-197,共3页Journal of Chinese Oncology

摘　　要：[目的]观察冷循环集束电极射频治疗晚期肝癌的效果。[方法]冷循环集束电极射频治疗38例晚期肝癌,术后每月复查CT观察病变区液化坏死和病灶缩小情况以及增强扫描是否强化、患者生存质量及AFP变化。[结果]术后1个月CT显示全部病灶均出现部分液化坏死及CT扫描不强化,3个月后CT扫描5例患者肿瘤完全坏死,其余大部分坏死。全部患者术后1个月KPS评分均提高10分以上。随访AFP变化与肿瘤毁损情况一致,术后CT复查病灶液化坏死范围大或病灶缩小明显的病例AFP下降显著。[结论]冷循环集束电极射频治疗是一种安全、有效、耐受性好的晚期肝癌治疗技术。初步结果显示该治疗能够提高患者生存质量、延长生存期,值得深入研究并推广。To evaluate clinical application of cluster electrode radio-frequency ablation(RFA)in the treatment of advanced liver cancer.Thirty-eight cases with advanced liver cancer were treated by cluster electrode RFA.The extent of liquefaction necrosis and the size of the tumors were observed by CTscan monthly.At the same time the quality of life and AFP levels were also evaluated.All lesions showed partial liquefaction necrosis and no enhanced area on the CTscan images at one month after treatment.CTscan showed complete liquefaction necrosis of the mass in five patients,partial necrosis in remainders.The KPS scores enhanced more than10score in all patients at one month.AFP level was consistent with the extent of tumor necrosis.After treatment,a dramatic decrease of AFPs was found in the patients who had obvious increased extent of liquefaction necrosis or decreased tumor lesions.[Conclusion]Cluster electrode radio-frequency is a safe,effective and tolerable technique for the treatment of advanced liver cancer.It is shown that the technique could improve the quality of life and prolong survival,so it is worth to further research and popularize.

关 键 词：肝肿瘤 射频疗法 介入疗法 

分 类 号：R735.7[医药卫生—肿瘤] R815[医药卫生—临床医学]