直肠癌术后复发再治疗的疗效探讨  

Retreatment of postoperative local recurrence of rectal cancer

作　　者：赵阳[1] 曹浩明[1] 楼荣灿[1] 陈贤贵[1] 李德川[1] 范永田[1] 

机构地区：[1]浙江省肿瘤医院外科六区,杭州310022

出　　处：《中华胃肠外科杂志》2003年第4期230-232,共3页Chinese Journal of Gastrointestinal Surgery

摘　　要：目的探讨直肠癌术后局部复发再治疗的疗效。方法对1990年1月至2000年12月收治的217例直肠癌根治术后复发患者不同治疗方法的疗效进行回顾性分析。结果217例患者中单纯手术(Ⅰ组)72例,手术切除加放疗(Ⅱ组)48例,单纯放疗(Ⅲ组)58例;未治疗(对照组)39例。Ⅰ、Ⅱ、Ⅲ组及未治疗组中位存活期分别为25、27、14及4个月。Ⅰ、Ⅱ组1、3年生存率显著优于Ⅲ组(P<0.01)。结论提高直肠癌复发患者疗效的关键是密切随访、早期诊断和实行手术或以手术为主的综合治疗。Objective To analyze the therapeutic effects of various treatments for local recurrence of rectal cancer after operation. Methods From Jan. 1990 to Dec. 2000,217 cases of local recurrent rectal cancer were studied. Seventy two cases underwent resection(groupⅠ), 48 were treated by resection combined with radiotherapy(group Ⅱ) and 58 patients received radiotherapy alone(group Ⅲ). The other 39 patients were untreated. Results The median survival times of the groupⅠ,Ⅱ,Ⅲ and untreated group were 25, 27, 14 and 4 months respectively. The survival rates of groupⅠ and Ⅱ were better than that of group Ⅲ significantly(P< 0 01). Conclusion Improvement can be expected from close follow up and earlier diagnosis. Synthetic therapy actively, including operation may result in good palliation and possible cure.

关 键 词：直肠癌 术后复发 疗效 放射治疗 手术治疗 综合治疗 

分 类 号：R735.37[医药卫生—肿瘤]