对中医药治疗原发性肝癌临床研究的方法学评价  

Methodological Evaluation of Clinical Study on Traditional Chinese Medicine Therapies for Primary Liver Carcinoma

作　　者：王喜[1] 刘庆[1] 岳小强[1] 侯凤刚[1] 邓伟哲[1] 顾伟[1] 沈旭波[1] 

机构地区：[1]第二军医大学附属长海医院,上海200433

出　　处：《湖南中医学院学报》2003年第4期50-52,共3页Journal of Hunan College of Traditional Chinese Medicine

摘　　要：目的了解近 5 0年来中医药治疗原发性肝癌临床研究的现状 ,并对其进行方法学评价。方法依据临床流行病学 DME方法学原则 ,对 1 949～ 2 0 0 2年间关于中医药治疗原发性肝癌的临床文献报道进行全面检索、筛选和方法学评价。结果共检索到中医药治疗原发性肝癌的文献题录 1 1 82条 ,实际检出全文 81 1篇 ,其中 9.74%的文献采用了随机对照试验 (RCT)的设计方案进行临床研究。但从总体上看 ,试验设计方案仍欠完善和严谨。结论目前在中医药治疗原发性肝癌的临床研究中 ,随机对照设计研究方案数量较少且总体质量较低 ,远远不能满足临床实践的需要 。?Objective To survey the status of clinical study on Traditional Chinese medicine(TCM) therapies for primary liver carcinoma (PLC) since 1949 to evaluate the data in a methodological way. Methods Based on the principles of clinical epidemiology and DME methodology, the clinical research literatures regarding TCM therapies for PLC from 1949 to 2002 were collected and evaluated. Results 811 articles were found from 1?182 pieces of title records concerning this kind of literatures, 9.74% of which took the design of randomized trial control(RCT). In an overall view, the methodology of trial design for these literatures was still unsatisfactory.Conclusions The current clinical studies on TCM therapies for PLC with RCT design are still less in quantity and lower in quality. The overall trial design level of clinical studies in this aspect need enhance urgently due to the demands of clinical practice. 〔

关 键 词：原发性肝癌 中医药学文献 质量评价 循证医学 

分 类 号：R735.7[医药卫生—肿瘤]