INTRA-OCULAR PRESSURE CHANGES AF-TER B-BLOCKER EYE DROPS INSTILLA-TION AND BICYCLE ERGOMETER EXER-CISE  

作　　者：V.E.Karabatakis T.E.Chatzibalis K.A.Kallinderis I.T.Bisbas K.I.Natsis A.Doudou S.G.Diafas A.Vermoud N.T.Stangos 

机构地区：[1]Eye Clinic, Aristotle University of Thessaloniki,Eye Clinic, Aristotle University of Thessaloniki,Eye Clinic, Aristotle University of Thessaloniki,Eye Clinic, Aristotle University of Thessaloniki,Eye Clinic, Aristotle University of Thessaloniki,Eye Clinic, Aristotle University of Thessaloniki,Eye Clinic, Papageolgiou Hospital, Greece,,JULES GONIN Hospital, Switzerland,Eye Clinic, Aristotle University of Thessaloniki

出　　处：《国际眼科杂志》2003年第1期122-122,共1页International Eye Science

摘　　要：Purpose: To evaluate the additive IOP effect of physical aerobic exercise (bicycle ergometer), in healthy individuals, after the in- stillation of b-blockers. Material: 20 healthy individuals. Methods: The IOP was measured before and 2 hours after the instillation of eye drops (b-blockers) in the right eye (OD) of the individuals.. The IOP was measured again within 5 minutes after the completion of physical exercise on a bicycle ergometer (about 10 minutes of duration - till exhaustion). Results: The instillation of b-blocker eye drops in the right eye was followed by an IOP decrease after 2 hours. The IOP decreased further more after the performance of the bicycle ergometer exercise. Mean IOP before the instillation of b-blocker. right eyes: 16.25, left eyes: 16.15. Mean IOP after the instillation of b-blocker. right eyes: 12.35 (decrease ranged from 3 to 5 mm Hg), left eyes: 14.20.. The IOP lowering effect after the bicycle ergometer exercise for the right eyes ranged from 1 to 5 mmHg. Mean IOP 10.20.Purpose: To evaluate the additive IOP effect of physical aerobic exercise (bicycle ergometer), in healthy individuals, after the in- stillation of b-blockers. Material: 20 healthy individuals. Methods: The IOP was measured before and 2 hours after the instillation of eye drops (b-blockers) in the right eye (OD) of the individuals.. The IOP was measured again within 5 minutes after the completion of physical exercise on a bicycle ergometer (about 10 minutes of duration - till exhaustion). Results: The instillation of b-blocker eye drops in the right eye was followed by an IOP decrease after 2 hours. The IOP decreased further more after the performance of the bicycle ergometer exercise. Mean IOP before the instillation of b-blocker. right eyes: 16.25, left eyes: 16.15. Mean IOP after the instillation of b-blocker. right eyes: 12.35 (decrease ranged from 3 to 5 mm Hg), left eyes: 14.20.. The IOP lowering effect after the bicycle ergometer exercise for the right eyes ranged from 1 to 5 mmHg. Mean IOP 10.20. As regards the left eye (without b-blocker medication) the IOP lowering effect of the bicycle ergometer exercise ranged from 1 to 5 mmHg. Mean IOP 12.50. Conclusions: The instillation of b-blockers has an IOP lowering effect in healthy individuals. The IOP decreases further more after the physical aerobic exercise (bicycle ergome-ter). The potential mechanism of the IOP decrease after a physical aerobic exercise was extensively discussed in various studies and remains under investigation. The present study is indicative that the b-sympathetic blockade does not exclude the influence of the exercise induced IOP lowering effect

关 键 词：Β-阻滞剂 眼药滴注 眼内压变化 自行车测力计 运动试验 IOP 

分 类 号：R775[医药卫生—眼科]