先天巨痣的临床、显微和超微结构观察  

The Observations of Clinic and Micro-, Uitrastructure of a Giant Congenital Nevus

作　　者：于甫[1] 卢戈[2] 喇杰廉 

机构地区：[1]甘肃省人民医院烧伤整形科 [2]兰州医学院组织学胚胎学教研室 [3]甘肃省肿瘤医院理疗科

出　　处：《兰州医学院学报》1992年第1期14-19,共6页Journal of Lanzhou Medical College

摘　　要：对一背心加领样先天巨痣进行了临床、显微和超微结构观察。发现表皮中含黑素细胞及黑素颗粒增多。真皮中载黑素细胞具基膜,产生圆形或不规则形载黑素颗粒,这些颗粒继而聚成载黑素复合体。含黑素颗粒及复合体的角质形成细胞、含载黑素颗粒及复合体的成纤维细胞、肥大细胞、雪旺细胞、神经束膜细胞及神经轴索等可统称为含黑素细胞。痣细胞团可沿真皮神经分布达皮下。痣细胞与含小泡的神经轴突膨大及肥大细胞相接触。本文对以上结构进行了讨论并为临床治疗提供理论依据。The observations of clinic and micro-,ultrastructure of a giant congenital nevus that looked like a 'vest with collar'were performed. It was found that the cells with melanin were more than normal within the epiderm, that the meLanophores within the dermis possessed the basement membrane and produced the round or irregular melanophoral granules which turned to aggregate the melanqphoral complex. The keratinocyte with melanosomes or melanin complex, and the fibroblast, mast cell, Schwann cell, perineurial cell and neural axone with melanophoral granules or complex, all could be named the melanin-contanning cell. The group of nevus cells could stretch along the dermis nerve to the hypodermis. The nevus pells could get in touch with the nerve axone expansion with the clear and dense vesicles, or in touch with the mast cell. The above structures were discussed and could provide a theory basis for the clinic therapy.

关 键 词：巨痣 黑素细胞 超微结构 

分 类 号：R361.3[医药卫生—病理学]