卷烟烟气中烟草特有的亚硝胺与挥发性N-亚硝胺的分析  

Analysis of Tobacco Specific Nitrosamines and Volatile Nitrosamines in Cigarette Smoke

作　　者：郭黎平[1] 金永明 张怡春 李宝[1] 杨良驹 陆士新[1] 

机构地区：[1]中国医学科学院肿瘤研究所,北京100021 [2]上海烟草(集团)公司技术中心

出　　处：《中国预防医学杂志》2003年第3期181-183,共3页Chinese Preventive Medicine

基　　金：上海烟草(集团)公司资助

摘　　要：目的　了解卷烟的烟气中烟草特有亚硝胺 (TSNA)和挥发性N -亚硝胺 (VNA)的情况。方法　以GC -TEA检测卷烟的烟气中的TSNA和VNA。结果　在卷烟烟气中检测到的VNA有NDMA ,NDEA ,NDMEA ,Npyr ,Npip ,NMBzA以及未知的N -亚硝胺 ,其含量在不同卷烟中有差别。在TSNA中检测到NNK ,NNN ,NAT以及未知的TSNA ,其中以NNK量最高 ;未检测到NAB。结论　卷烟的烟气中存在致癌的N -亚硝胺 ,降低烟草及卷烟烟气中N -亚硝胺含量是预防疾病的重要战略措施。Objective To understand the presence of tobacco specific nitrosamines(TSNA)and volatile N-nitrosamines(VNA)in cigarette smoke in China. Methods The tobacco specific nitrosamines and volatile N-nitrosamines in cigarette smoke were analyzed using GC-TEA analysis. Results We found the volatile N-nitrosamines,NDMA,NDEA,NDMEA,Npyr,Npip,NMBzA and unknown nitroso compound in cigarettes smoke,and the contents in various cigarettes were significantly different.We also found the TSNA,such as NNK,NNN,NAT and unknown nitroso compound in cigarettes smoke.Among TSNAs,the content of NNK was the highest.NAB has not been detected. Conclusions The carcinogenic N-nitrosamines are presented in the cigarete smoke,and decreasing the contents of N-nitrosamines in tobacco and in cigarette smoke is an important strategic measurement for preventing diseases.

关 键 词：卷烟烟气 挥发性N-亚硝胺 烟草特有亚硝胺 致癌 检测 

分 类 号：R114[医药卫生—卫生毒理学]