光学相干断层成像术与神经纤维层彩色立体照相在青光眼检查中应用比较  

The comparison of detecting RNFL using optical coherence tomography with RNFL color stereoscopic photography

作　　者：王梅[1] 葛坚[2] 刘嫣芬[1] 蓝育青[1] 骆荣江[1] 陈秀琦[2] 

机构地区：[1]中山大学附属第二医院眼科,510120 [2]中山大学中山眼科中心

出　　处：《中国实用眼科杂志》2003年第8期596-598,共3页Chinese Journal of Practical Ophthalmology

摘　　要：目的 :评价光学相干断层成像术 (OCT)测量视网膜神经纤维层 (RNEL)厚度在检测青光眼RNFL缺损中的作用。方法 :采用配对法 ,对 3 0例 43眼已确诊的原发性开角型青光眼均予OCT和RNFL彩色立体照相 ,对RNFL分别进行定量与定性的检查。结果 :OCT定量测量RNFL厚度在青光眼中的异常率为 81 40 % ,RNFL彩色立体照相的异常宰为 67 44 % ,经 χ2 检验 ,差异无显著性 (P >0 0 5 )。二种方法对RNFL缺损部位检出的一致率为 5 8 14 % ,κ值为 0 43。结论 :在青光眼RNFL病变的检测中 ,OCT对RNFL厚度的测量与RNFL彩色立体照相进行对照 ,具有较好的敏感性与一致性 ,可作为青光眼RNFL病变的有效检测手段。Objective:To estimate the general power of optical coherence tomography (OCT) in the detection of open-angle glaucoma on the item of retinal nerve fiber layer (RNFL) thickness,compared with RNFL color stereoscopic photography. Methods:30 patients (43 eyes) with primary open-angle glaucoma underwent OCT and RNFL color stereoscopic photography. Results:The abnormal rates of RNFL thickness measured by OCT and RNFL color stereoscopic photography in glaucoma were 81.4% and 67.44%,respectively (P>0.05).The agreement between both methods was 58.14%,and κ (kappa) value is 0.43. Conclusions:The sensitivity and agreement of OCT in the examination of RNFL is quite good compared with RNFL color stereoscopic photography for the detection of glaucoma.

关 键 词：青光眼 光学相干断层成像术 神经纤维层彩色立体照相 诊断 

分 类 号：R775.1[医药卫生—眼科]