大鼠颈部及腹部同种异体心脏移植模型的比较  

Comparison of rat allo-cardiac transplantation model in cervical and abdominal site

作　　者：熊海波[1] 温浩[1] 

机构地区：[1]新疆医科大学第一附属医院普外科,新疆乌鲁木齐830054

出　　处：《新疆医科大学学报》2003年第4期355-357,共3页Journal of Xinjiang Medical University

摘　　要：目的:探讨大鼠颈部和腹部心脏移植模型的优缺点及手术操作的改进。方法 :通过建立模型的初期阶段和后期阶段 ,从手术时间及并发症方面比较大鼠颈部和腹部心脏移植的特点。结果:在建立模型的初期 ,并发症发生率较高 ,颈部模型静脉回流不畅、局部积液的发生率较高 ;腹部模型静脉回流较佳 ,腹腔抗感染能力较强 ,但可发生肠梗阻及下肢瘫痪。在建立模型的成熟阶段 ,各种并发症发生率明显降低 ,但颈部模型静脉回流不畅和局部积液的发生率仍高于腹部模型。 结论 :两种模型有各自的优缺点 ,经过一定时期的训练 。Objective: To compare rat cardiac transplantation models in cervical and abdominal site and observe speciality of the two models. Methods: To compare heart transplantation models by observing operating time and complication in different stage. Results: Complication decreased obviously with improvement of micro surgical techenique in the second stage, the incidence of some complications in cervical model was higher than that in abdominal model. Conclusion: Cervical and abdominal cardiac transplantation models are reliable animal models for the study of transplantation, but the two models have both virtues and shortcomings respectively.

关 键 词：大鼠 移植 模型 并发症 心脏 

分 类 号：R-332[医药卫生] R617