高强度聚焦超声肿瘤治疗仪控制系统设计及功能测试  

Design and test of hardware controller for a tumor therapy instrument using high intensity focused ultrasound

作　　者：谢志行[1] 李丽平[1] 严加勇[1] 寿文德[1] 孙俊霞[1] 林卫平[1] 钱德初[1] 王鸿樟[1] 杨渊峰[2] 徐叶青[2] 王国民[2] 沈祺茂 石珍龙 

机构地区：[1]上海交通大学生物医学工程系,上海200030 [2]复旦大学附属中山医院,上海200032 [3]海鹰企业集团有限责任公司,无锡214061

出　　处：《声学技术》2003年第3期153-156,共4页Technical Acoustics

摘　　要：用高强度聚焦超声(HIFU)治疗肿瘤近年来受到越来越多的关注。目前已有的HIFU肿瘤治疗仪采用的是湿式设计,将病灶部位浸入水槽内,探头由下至上进行治疗。这样不仅不方便且对一些特殊部位——如颈部无法进行治疗。文章介绍的HIFU肿瘤治疗仪成功采用干式设计,将探头放入一水囊内,由上至下经水囊耦合对病灶区进行治疗,增加了对控制系统的控制精度、速度与可靠性的要求。文章首次设计了一块DSP电路板作为可独立运行的HIFU前端控制器,在该板上集成了控制步进电机、脉冲编码器、超声功率放大器及实时控制策略运算等HIFU肿瘤治疗所有控制功能。DSP板可通过RS232接口与后端PC主机通讯,并经过光电隔离、电平转换后与步进电机等外围器件连接。该仪器已通过了功能测定,并已进行了离体试验,测定与试验结果令人满意。Treatment of tumor with high intensity focused ultrasound(HIFU)is a new method developed in recent years, which has received increasing attention. Presently available tumor therapy instruments treat patients by immerging the target into water and with the transducer deployed beneath the target and emitting upward. This is not only inconvenient, but also impractical in treating certain special body parts such as cervix. In this paper, a HIFU tumor therapy instrument is designed by placing the transducer into a water bag on top of the patient and transmitting downward. This requires higher precision, speed and reliability of the control system. A DSP based board is developed as an independent front-end controller. All the functions needed by the instrument including control of step-motors, pulse-coders and ultrasound power amplifiers, and computation of real-time control-strategy are integrated on the board. The DSP board communicates with the host PC via a standard RS232 interface, and is connected with peripherals such as step-motors, pulse-coders, etc. , via photoelectric isolation and voltage conversion circuits. The instrument has passed both laboratory test and vitro-test in hospital with satisfactory results.

关 键 词：高强度聚焦超声 肿瘤治疗仪 控制系统 设计 功能测试 HIFU DSP电路板 

分 类 号：R730.5[医药卫生—肿瘤] TB559[医药卫生—临床医学]