青光眼病人房水心钠素含量与眼压变化的研究  

An Analysis of the Relationship of the Contents of Atrial Natriuretic Peptide (ANP) in Aqueous Humor to the Variety of Intraocular Pressure Measured With Glaucoma Patients

作　　者：曾祥云[1] 王辉[1] 唐爱东[1] 文道源[1] 蒋贻平[1] 罗瑛[1] 文为杰[1] 袁思奇[1] 刘春棋[2] 刘琳琳[1] 彭文轩[1] 刘万蓉[1] 

机构地区：[1]赣南医学院附属医院眼科 [2]赣南医学院附属医院检验科,江西赣州341000

出　　处：《赣南医学院学报》2003年第3期259-261,共3页JOURNAL OF GANNAN MEDICAL UNIVERSITY

基　　金：江西省卫生厅资助项目

摘　　要：目的 :探讨青光眼病人房水心钠素 (ANP)含量与眼压变化的关系。方法 :利用放射免疫分析方法测定房水ANP含量。结果 :房水ANP平均含量 :术前高眼压组 (A组 ) 2 6 6 .5 6± 18.2 0 pg/ml;术前眼压控制组 (B组 ) 6 9.9± 9.99pg/ml;对照组 (C组 ) 5 4.4 1± 7.4 9pg/ml。三组病人的术前眼压和房水ANP含量均有显著性意义 (P <0 .0 0 1) ;不同类型的青光眼病人房水ANP含量差异无显著性意义 (P >0 .0 5 )。结论 :青光眼病人当眼压升高时可导致房水ANP含量的明显改变 ,其含量随眼压的升高而增加 。Objective:Inquiry into a relationship of the contents of ANP in aqueous humor to the variety of intraocular pressure measured with glaucoma patients.Method:The analytic method of the radiative immunity was used to measure the contents of ANP in aqueous humor.Result:The average of the contents of ANP in aqueous humor were 266.56±18.2pg/ml in high intraocular pressure group (A group)before operation,269.9±9.99pg/ml in intraocular pressure-controlled group (B group) before operation and 54.41±7.49pg/ml in matched control group(C group).The variation in contents of ANP in aqueous humor for all groups had the extraordinary signification( P <0.001).There was not a signification ( P >0.05) for the contents of ANP in aqueous humor among different types of glaucoma patients.Conclusion:The concentration of ANP in aqueous humor is increasing remarkablyduring the rise of intraocular pressure with glaucoma patient,it suggests that the kind of circulating hormone (ANP) may regulate intraocular pressure and participate in the rise of intraocular pressure or the outbreak process of glaucoma.

关 键 词：心钠素 眼压 青光眼 

分 类 号：R775[医药卫生—眼科]