VEEG和ECoG在伴有海马病变的难治性癫癎外科治疗中的价值  

Value of VEEG and ECoG in surgical treatment of intractable epilepsy with hippocampal abnormality

作　　者：史增敏[1] 白勤[1] 谭郁玲[1] 

机构地区：[1]北京市神经外科研究所,北京100050

出　　处：《临床神经电生理学杂志》2003年第3期144-146,共3页Journal of Clinical Electroneurophysiology

摘　　要：目的 :探讨同步录像脑电图 (VEEG)和皮质脑电图 (ECoG)在伴有海马病变的难治性癫诊断中的应用价值。方法 :回顾性分析 2 6例难治性癫患者临床发作类型、术前MRI与VEEG检查、术中ECoG及深部电极脑电图监测结果 ,术后病理检查证实所有患者海马均有病变。结果 :在连续或超过 2 4hVEEG监测中 ,18例有临床发作 ( 6 9% ) ,其中 1例简单部分性发作 ,6例复杂部分性发作 ,9例全身强直发作 ,2例失神发作。各例均可见样波活动 ,多数集中于颞叶。术中ECoG监测颞区皮质均有棘波发放 ( 10 0 % ) ,深部电极监测海马区有波放电 2 5例 ( 96 % )。结论Objective: To explore the applicational value of Video-EEG(VEEG) and ECoG in the diagnosis of intractable epilepsy with hippocampal abnormality.Methods: The clinical seizure types,preoperative cranial MRI,VEEG findings and intraoperative ECoG and deep electrode EEG monitoring was analyzed retrospectively in 26 patients with intractable epilepsy.Hippocampal abnormality was found in postoperative pathological examination in all the 26 ones.Results:Clinical seizure were recorded in 18 patients during continous VEEG monitoring more than twenty-four hours,including simple partial seizure in 1 patient,complex partial seizures in 6 patients,generalized seizure in 9 patients and absence seizure in 2 patients.Epileptiform discharges actiyity were found in each one and the majority of them were found in temporal lobe.ECoG monitoring found focal epileptiform discharges in the cortex of the temporal region in all the patients and the deep electrode EEG found epileptiform discharges in hippocampal region in 25 patients(96%).Conclusions:VEEG and ECoG might be of important value in the diagnosis and focus localization of intractable epilepsy with hippocampal abnormality.

关 键 词：VEEG ECOG 海马病变 难治性癫痫 外科治疗 同步录像脑电图 皮质脑电图 

分 类 号：R742.1[医药卫生—神经病学与精神病学] R741.044[医药卫生—临床医学]