子宫动脉栓塞治疗子宫肌瘤疗效因素分析  

Influential factors to therapeutic efficacy of uterine artery embolization in the treatment of uterine fibroids

作　　者：周顺科[1] 李少波[1] 张子曙[1] 张洪文[2] 肖恩华[1] 朱美香[1] 

机构地区：[1]中南大学湘雅二医院放射科,长沙410011 [2]中南大学湘雅二医院妇产科,长沙410011

出　　处：《湖南医科大学学报》2003年第4期409-411,共3页Bulletin of Hunan Medical University

摘　　要：目的 :探讨子宫动脉栓塞术 (uterinearteryembolizationUAE)对子宫肌瘤的治疗效果 ,并对影响疗效的因素进行分析。方法 :32例症状性子宫肌瘤患者 ,经超选择性插管双侧子宫动脉内注入PVA微粒栓塞治疗 ,术后 6个月随访复查 ,观察患者临床症状改善和子宫及肌瘤体积变化情况。结果 :UAE术后患者子宫出血症状改善最为明显 ,栓塞后 6个月肌瘤体积平均缩小 5 5 .6 %,肌壁间和黏膜下肌瘤的临床症状改善和体积缩小较浆膜下肌瘤明显。结论 :双侧子宫动脉栓塞治疗子宫肌瘤是一种安全有效的新方法 ;其疗效与栓塞术后肌瘤血管的重新构建 ,肌瘤类型 ,血供状态 ,子宫动脉单双侧栓塞等多种因素有关。Objective To investigate the therapeutic efficacy of uterine artery embolization in the treatment of uterine fibroids and to analyse the influential factors to the therapeutic efficacy. Methods Thirty-two patients with symptomatic uterine myomas were treated by superselective catheterization and embolization of bilateral uterine arteries using PVA particles . Patients were followed for 6 months after uterine artery embolization. Baseline symptoms and the volume of the fibroids were used as parameters to evaluate the therapeutic efficacy.Influential factors to therapeutic efficacy were analyzed. Results The clinical symptoms, especially heavy menstrual bleeding, were improved markedly. An average of 55.6% volume reduction of the fibroids was achieved during the 6 month follow-up. The submucosal and intramural location of the myomas reduced more in the volume compared with that of the subserosal location.Conclusion Selective uterine artery embolization is effective for uterine myoma. Influential factors to the therapeutic efficacy may include: postprocedural vascular reconstruction in the fibroid, location of the fibroid, hemodynamic status of the fibroid, and the mode of embolization (unilateral or bilateral).

关 键 词：子宫动脉栓塞 治疗 子宫肌瘤 子宫动脉 放射学 介入性 

分 类 号：R737.33[医药卫生—肿瘤]