凝血酶治疗急性消化道出血的临床观察  

Hemostasis with thrombin to hemorrhage of digestive tract

作　　者：刘均平[1] 张占云[1] 梅咏丽 范南[1] 

机构地区：[1]宁夏医学院附属医院消化内科

出　　处：《宁夏医学杂志》1992年第4期222-224,共3页Ningxia Medical Journal

摘　　要：急性消化道出血是内科常见急症,病死率8～13.%。传统疗法多采用 H_2受体拮抗剂、血管收缩剂、孟氏液治疗。我科于1990～1991年用凝血酶与 H_2受体拮抗剂、血管收缩剂、孟氏液合用治疗急性消化道出血患者22例,同时以1989年传统疗法治疗的急性上消化道患者21例做对比,现报告如下。资料和方法一、资料治疗组:男17例,女5例。平均年龄54.7岁,<49岁8例,>50岁14例。其中肝硬化合并上消化道出血8例。43 patients were divided into two groups at random.Each group inclu- ded peptic ulcer and hepatocirrhosis. GroupA were treated with thrombin, antagonstof histamine H2 recepter and Monsell's solution.Group B were tre- ated with the above drugs except thrombin.Effective rate of group A is 95.5%,group B is 63.6%.There is significant difference between two groups.Thrombin can directly act on fibongen in blood and promote it turning into fibrin,speed up solidifying of blood.The goal of haemostasis is atta- ined thereby.It comes to the conclusion that thrombin is effective to hemor- rhage of digestive tract.

关 键 词：消化道出血 凝血酶 

分 类 号：R570.5[医药卫生—消化系统]