早期胃癌微创手术的近期和远期疗效研究  

A Retrospective Study Comparing Perioperative Results and Long-term Survival between Laparoscopyassisted Gastrectomy and Open Procedures for Gastric Cancer

作　　者：张鹏程[1] 

机构地区：[1]河北北方学院附属第一医院,075000

出　　处：《实用癌症杂志》2015年第4期518-520,523,共4页The Practical Journal of Cancer

摘　　要：目的评估腹腔镜胃癌根治术的近期及远期疗效。方法将100例行胃癌微创术的病例,随机分为腹腔镜胃癌根治术(LRG)和开腹胃癌根治术(ORG)各50例,比较两组患者的手术时间、术中失血量、术后恢复情况、并发症、术后病理及远期随访结果。结果 LRG组手术时间长于ORG组(P<0.05),但出血量较少(P<0.05),术后肛门排气时间及住院天数短(P<0.05)。2组淋巴结清扫数目相比差异无统计学意义(P>0.05)。2组间术后总体并发症发生情况相比差异无统计学意义(P>0.05)。LRG组和ORG组5年总生存率分别为43.85%、41.39%,差异无统计学意义(P>0.05);患者预后与年龄、性别、手术方法和术后并发症无显著相关性(P>0.05)。结论腹腔镜辅助胃癌根治术微创效果明显,术后恢复快,与开腹手术相比并不会增加患者术后远期复发和死亡的风险。Objective To evaluate the short and long-term outcomes of laparoseopy·assisted gastrectomy for gastric cancer.Methods After studying the patients demographic data,extent of gastrectomy and lymphadenectomy,as well as differentiation and tumor TNM stage,50 patients who underwent LRG were individually matched to 50 patients who underwent ORG.The operative time,intraoperative blood loss,postoperative recovery,complications,pathological findings and follow-up data were compared between the two groups.Results The mean operative time was significantly longer in the LRG group than in the ORG group,whereas intraoperative blood loss was significantly lower.In addition,there was a significant reduction in the time to first flatus and postoperative hospital stay.There was no significant diference between the LRG group and ORG group with regard to the number of harvested lymph nodes and overall postoperative complications.The 5-year disease-free survival rates and overall survival rates were 43.85%,41.39%.Conclusion LRG is suitable and minimally invasive for treating gastric cancer.Compared to ORG,the LRG does not increase the risk of recurence and mortality after surgery.

关 键 词：早期胃肿瘤 微创术 生存状况 

分 类 号：R735.2[医药卫生—肿瘤]