全麻支撑喉镜联合电子喉镜行射频治疗早期声门癌的临床观察  

Clinical Observation of Anesthesia Laryngoscope Combined with Electronic Laryngoscope in Radio Frequency for Early Glottic Carcinoma

作　　者：王浩明[1] 江洋[2] 

机构地区：[1]湖北省黄冈市浠水县人民医院,438200 [2]武汉大学人民医院,430060

出　　处：《实用癌症杂志》2015年第6期868-870,共3页The Practical Journal of Cancer

摘　　要：目的探讨全麻支撑喉镜联合电子喉镜行射频揭盖术治疗早期声门癌的临床效果。方法 80例会厌囊肿患者随机分为观察组与对照组,每组40例。观察组采用射频+切除+射频的手术方法,对照组采用单纯的手术进行治疗。对比2组患者的嗓音学参数,手术时间,术中出血量,治愈率和术后复发率。结果嗓音学参数结果显示观察组患者的振幅微扰,基频微扰,标准规范化噪声能量,和谐噪比的嗓音学参数显著优于对照组,差异有统计学意义(P<0.05),基频的差异无统计学意义(P>0.05)。观察组患者的手术时间(101.7±12.2)min和术中出血量(9.0±2.3)m L均显著低于对照组(135.4±12.6)min与(14.6±3.1)ml,差异具有统计学意义(P<0.05)。术后3个月在支撑喉镜下检查创面均基本愈合,患者声带运动正常,发声较好。观察组患者的3年复发率为2.5%,显著低于对照组的17.5%;5年复发率为12.5%,显著低于对照组的37.5%,差异均具有统计学意义(P<0.05)。3年生存率和5年生存率2组差异无统计学意义(P>0.05)。结论全麻支撑喉镜联合电子喉镜行射频揭盖术治疗早期声门癌手术时间短,嗓音损伤小,出血量少,复发率低,值得临床推广。Objective To explore the clinical efficacy of anesthesia laryngoscope combined with electronic laryngoscope in radio frequency( RF) for early glottic carcinoma. Methods 80 cases of epiglottic cysts were randomly divided into the observation group and the control group,each with 40 cases. The observation group received RF + resection + RF,the control group received simple resection treatment. Voice parameters,operation time,intraoperative blood loss,postoperative recurrence rates and cure rates of the 2 groups were compared. Results Voice parameters showed that amplitude perturbation,jitter,standard normalized noise energy,voice harmonious noise ratio parameters in the observation group were significantly better than those of the control group,the difference was statistically significant( P < 0. 05),there had no significant differences in the fundamental frequency( P > 0. 05). The operation time( 101. 7 ± 12. 2) min and the amount of bleeding( 9. 0 ± 2. 3) m L in the observation group was significantly lower than those of the control group( 135. 4 ± 12. 6) min and( 14. 6 ± 3. 1) m L,the difference was statistically significant( P < 0. 05). 3 months after surgery under laryngoscope wound was healed,vocal cord movement was normal,sound was good. 3-year recurrence rate in the observation group was 2. 5%,which was significantly lower than that of the control group17. 5%,5-year recurrence rate was 12. 5%,which was significantly lower than that of the control group 37. 5%,there had significant difference( P < 0. 05),there had no significant difference in the 3-year survival rate and 5-year survival rate between the groups( P > 0. 05). Conclusion Anesthesia laryngoscope combined with electronic laryngoscope RF marsupialization for early glottic carcinoma has shorter operation time,smaller voice injury,less bleeding,and low recurrence rate,it is worthy of clinical application.

关 键 词：支撑喉镜 电子喉镜 射频 早期声门癌 

分 类 号：R739.65[医药卫生—肿瘤]