等离子体对裸鼠荷人源黑色素瘤的抑制作用观察  

Observation of Inhibitory Effect on Plasma to Melanoma Transplanted from Human in Nude Mice

作　　者：蒋立群 李志满[2] 吴建军[3] 

机构地区：[1]深圳市福田区妇幼保健院,深圳518048 [2]吉林大学实验动物中心,长春130021 [3]吉林大学第二医院,长春130041

出　　处：《实验动物科学》2015年第3期30-32,共3页Laboratory Animal Science

基　　金：吉林省科技发展计划资助项目(No:20122145)

摘　　要：目的测试等离子体(APNP)对恶性黑色素瘤的抑制效果。方法建立B16恶性黑色素瘤的裸鼠移植模型12只,随机分为等离子体治疗组和空白对照组。定期测量肿瘤的长径和短径并观察动物的健康状态,计算肿瘤体积和抑瘤率。结果治疗组的肿瘤抑制率为88%。结论适量的等离子体具有有效抑制恶性黑色素瘤的生长能力。Objective To investigate the inhibitory effect of plasma( APNP) on malignant melanoma. Method Twelve nude mouse models were established by transplanting the B16 malignant melanoma,and then were randomly divided into two groups,the plasma treatment group and the control group. Animal health was monitored,and the lengths and the widths of tumors were examined regularly. Tumor volumes and inhibition rates were calculated respectively. Result The inhibition rate was 88% in the treatment group. Conclusion Plasma treatment at a proper dose can inhibit the growth of melanoma effectively.

关 键 词：等离子体 裸鼠移植模型 抑瘤率 

分 类 号：R739.5[医药卫生—肿瘤]