重庆地区健康幼儿肺炎链球菌携带率及耐药性的调查分析  

Investigation and Analysis of Total Rate and Drug Susceptibility of Streptococcus Pneumonia Isolated from Healthy Children in Chongqing

作　　者：曾佑群[1] 

机构地区：[1]重庆医科大学儿童医院,重庆400014

出　　处：《实用医技杂志》2003年第8期832-833,共2页Journal of Practical Medical Techniques

摘　　要：目的 :调查重庆地区健康幼儿的肺炎链球菌携带率及其对 8种抗菌药物的体外抗菌活性 ,用以评估社区耐药发生率及预测临床株耐药性。方法 :采用琼脂扩散法与定量琼脂稀释法。结果 :从 4 0 0例健康幼儿鼻腔中取鼻咽拭子 ,分离到 76株肺炎链球菌 ,幼儿携带率为 19% ,通过定量琼脂稀释法确认 76株肺炎链球菌中有 6株耐青霉素肺炎链球菌 (Pencillin Resistance to Pneumonia,PRP)。结论 :与其他地区相比 ,重庆地区健康幼儿的肺炎链球菌携带率不高 ,但随着抗生素的广泛使用 ,耐药株有可能增加 。Objective To investigate the total rate and drug susceptibility of streptococcus pneumonia (SPN) isolated from the healthy children in Chongqing. In vitro antimicrobial activities were determinied of 8 antimicrobial agents against SPN, so as to eveluate the incidence of drug-resistance in community and guide the clinical treatment. Methods K-B agardilution. Results Of the 400 healthy children, 76 SPN strains were isolated (the total rate 19 % and there were 6 penicillin resistance to pneumonia (PRP ) strains. Conclusion The total rate of SPN in healthy children was not high in Chongqing, but doctor should realize that the incidence of penicillin-resistance may increase with the extensive use of antimicrobial agents.

关 键 词：重庆 健康幼儿 肺炎链球菌 携带率 耐药性 琼脂扩散法 定量琼脂稀释法 抗生素 

分 类 号：R725.6[医药卫生—儿科]