胃癌患者术中腹腔灌洗细胞学检测的临床研究  

Clinical study on peritoneal lavage for cytological examination in patients with gastric cancer

作　　者：秦贤举[1] 陈德杰[2] 吴军[1] 陈问谭[1] 

机构地区：[1]上海复旦大学附属中山医院肿瘤中心,200052 [2]武汉大学中南医院外科

出　　处：《肿瘤防治研究》2003年第5期406-407,共2页Cancer Research on Prevention and Treatment

摘　　要：目的　探讨腹腔游离癌细胞与胃癌的侵润深度、浆膜受侵面积及病理类型等之间的相互关系。方法　对 16 3例胃癌患者行术中腹腔灌洗细胞学检查找游离癌细胞。结果　总的灌洗阳性率为2 6 .3%。不同侵犯深度 (T1～T4)阳性率分别为 0、13.3%、2 9.8%、5 3.8% ;胃浆膜受侵面积≤ 10cm2 者阳性率为 12 .6 %、11～ 2 0cm2 者 2 1.9%、2 1～ 30cm2 者 4 2 .1%、≥ 31cm2 者高达 6 6 .6 %。结论　胃癌腹腔游离癌细胞的阳性率与肿瘤侵润深度、浆膜受侵面积及病理类型等直接相关。Objective To explore the clinical value of intraoperative peritoneal lavage for cytological examination in patients with gastric cancer. Methods More than 100ml peritoneal fluid were collected before intraoperative detection and then sent for free cancer cells(FCC) in 163 patients with resectable gastric cancer. Results The positive rate of FCC is 26.3% in 163 patients and T_1:0、T_2: 13.3% 、T_3: 29.8% 、T_4: 53.8% . The positive rate of FCC with different infiltration area of gastric serosa are ≤10cm 2: 12.6% 、11～20cm 2: 21.9% 、21～30cm 2: 42.1% 、≥31cm 2: 66.6% . With different type of the histopathology are 13.9% with good differentiation and 37% with poor differentiation. Conclusion The positive rate of FCC is concerned with tumor infiltration depth, infiltration area of gastric serosa and type of the histopathology.

关 键 词：胃癌 腹腔灌洗 细胞学检测 预后 

分 类 号：R735.2[医药卫生—肿瘤]