抗栓灵含片的制备及稳定性考察  

Stduy on the Preparation and Stability Anti—thrombin Sublingual Tablts

作　　者：徐凤霞 姜华[2] 

机构地区：[1]哈高科白天鹅药业集团有限公司,150070 [2]哈药集团制药总厂

出　　处：《黑龙江医药》2003年第5期444-445,共2页Heilongjiang Medicine journal

摘　　要：目的:该试验为了改善传统工艺颗粒流动性差,片面易产生印斑,口感差等缺点。方法:以透明质酸酶为透皮吸收促进剂,配以甘露醇、糊精和羟丙纤维素等辅料制备而成的无糖型产品。结果:解决了糖尿病患者增加血糖来源的副作用问题。结论:此工艺制得片剂的稳定性明显优于以乳糖、山梨酸等为辅料制得的片剂,该制备工艺可行。Objection:The experimental method improres traditional process weakness of grain flowing difference tablets side spot,difference sense in month.Methods:The tablets is a kind of no sweets product which is prepared from percolating absorption accelerators Hyal- wronidase,the second material Mannitol,pextrin,Hyrpolose.Results:The process solves prob- lems which increase side effect of blood sugar source.Conclusion:This production technology which better than before is practical.

关 键 词：抗栓灵含片 制备 稳定性 甘露醇 糊精 

分 类 号：R973.2[医药卫生—药品]