A Novel Fluorescent Probe for Lead Ions  

作　　者：Ming SUN, Di Hua SHANG GUAN, Hui Min MA, Li Hua NIE, Xiao Hua LIShao Xiang XIONGLaboratory of Chemical Biology, Center for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080 

出　　处：《Chinese Chemical Letters》2003年第10期1024-1026,共3页中国化学快报（英文版）

基　　金：supported by the NNSF of China(No.20175031,No.20035010)

摘　　要：A new fluorescent probe for lead ions,p-nitrophenyl 3H-phenoxazin-3-one-7-yl phosphoric acid (NPPA), has been synthesized by linking resorufin (serving as a fluorophore and electron acceptor) to p-nitrophenol (serving as a fluorescence quencher and electron donor) through phosphodiester bonds. When NPPA was irradiated with light, intramolecular fluorescence self-quenching took place due to the PET (photoinduced electron transfer) from the donor to the acceptor. However, upon addition of PbII, the phosphate ester bonds in the probe were cleaved and the fluorophore was released, accompanying the retrievement of fluorescence.A new fluorescent probe for lead ions,p-nitrophenyl 3H-phenoxazin-3-one-7-yl phosphoric acid (NPPA), has been synthesized by linking resorufin (serving as a fluorophore and electron acceptor) to p-nitrophenol (serving as a fluorescence quencher and electron donor) through phosphodiester bonds. When NPPA was irradiated with light, intramolecular fluorescence self-quenching took place due to the PET (photoinduced electron transfer) from the donor to the acceptor. However, upon addition of PbII, the phosphate ester bonds in the probe were cleaved and the fluorophore was released, accompanying the retrievement of fluorescence.

关 键 词：Fluorescent probe LEAD PHOSPHODIESTER hydrolysis. 

分 类 号：O627[理学—有机化学]